IRF3 (human recombinant)
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- $534
- Product name: IRF3 (human recombinant)
- CAS:
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- MW: 0
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- Synonyms:IRF3 (human recombinant)
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Brand
- Cayman Chemical
Package
- 100μg
- ManufacturerCayman Chemical
- Product number22811
- Product descriptionIRF3 (human, recombinant) ≥85%asestimatedbySDS-PAGE
- Packaging100μg
- Price$534
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Cayman Chemical | 22811 | IRF3 (human, recombinant) ≥85%asestimatedbySDS-PAGE | 100μg | $534 | 2026-04-30 | Buy |
Properties
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Description
Interferon regulatory factor 3 (IRF3) is a member of the IRF family. It plays a crucial role in activation of innate immunity and inflammation in response to viral infection, functioning as a molecular switch for antiviral activity.1,2,3,4,5 Double-stranded RNA generated during a viral infection leads to IRF3 activation by serine/threonine phosphorylation by TBK1 or IKBKE kinases, which induces a conformational change leading to its dimerization, nuclear localization, and association with CREBBP.1,2,3,6 The complex, known as DRAF1, activates transcription interferons alpha and beta, as well as other interferon-induced genes.1,6 These genes play a critical role in type 1 interferon (IFN)-dependent immune response.5 A recent study shows phosphorylation of innate immune adaptor proteins MAVS, STING, and TRIF recruits and specifies IRF3 phosphorylation and activation by the serine/threonine-protein kinase TBK1, thereby inducing the production of type-1 interferons.2,4,7WARNING This product is not for human or veterinary use.More related product prices