Ingenol mebutate
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- $46 - $2750
- Product name: Ingenol mebutate
- CAS: 75567-37-2
- MF: C25H34O6
- MW: 430.53
- EINECS:
- MDL Number:MFCD22683801
- Synonyms:Ingenol-3-O-angelate;Ingenol Mebutate, >98%;Ingenol 3-mebutate;Ingenol-3-O-angelate 75567-37-2;PEP005; INGENOL MEBUTATE; I3A;Ingenol Mebutate (PEP005);(2Z)-2-Methyl-2-butenoic acid (1aR,2S,5R,5aS,6S,8aS,9R,10aR)-1a,2,5,5a,6,9,10,10a-octahydro-5,5a-dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1H-2,8a-methanocyclopenta[a]cyclopropa[e]cyclodecen-6-yl ester;(1aR,2S,5R,5aS,6S,8aS,9R,10aR)-5,5a-Dihydroxy-4-(hydroxymethyl)-1,1,7,9-tetramethyl-11-oxo-1a,2,5,5a,6,9,10,10a-octahydro-1H-2,8a- methanocyclopenta(a)cyclopropa(e)cyclodecen-6-yl (2Z)-2-methylbut-2-enoate
65 prices
Selected condition：
Brand
- ACHEMBLOCK
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- Arctom
- AvaChem
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Thermo Scientific Chemicals
- TRC
Package
- 500μg
- 1mg
- 2mg
- 2.5mg
- 5MG
- 20mg
- 10mM*1mLinDMSO(Solution)
- 10MG
- 25mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 50mg
- 100mg
- 250mg
- ManufacturerACHEMBLOCK
- Product numberV155991
- Product descriptionIngenol 3-Angelate 98%
- Packaging5MG
- Price$250
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberV155991
- Product descriptionIngenol 3-Angelate 98%
- Packaging10MG
- Price$350
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0012-M005
- Product descriptionIngenol-3-angelate ≥97%(HPLC)
- Packaging5mg
- Price$350
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0012-M001
- Product descriptionIngenol-3-angelate ≥97%(HPLC)
- Packaging1mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0012-M005
- Product descriptionIngenol-3-angelate ≥97%(HPLC)
- Packaging5mg
- Price$420
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3737AH
- Product descriptionIngenol3-angelate
- Packaging10mg
- Price$977
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005276
- Product descriptionINGENOL 3-ANGELATE 95.00%
- Packaging1MG
- Price$258.3
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging10mM*1mLinDMSO(Solution)
- Price$268
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging10mM*1mLinDMSO(Solution)
- Price$268
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging5mg
- Price$245
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging5mg
- Price$245
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$255
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging10mM*1mLinDMSO(Solid+Solvent)
- Price$255
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberAB2726
- Product descriptionIngenol 3-Angelate 98%(HPLC)
- Packaging10mg
- Price$312
- Updated2026-05-26
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging1mg
- Price$77
- Updated2026-05-25
- Buy
- ManufacturerArctom
- Product numberHY-B0719
- Product descriptionIngenol Mebutate 99.65%
- Packaging1mg
- Price$77
- Updated2026-05-26
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| ACHEMBLOCK | V155991 | Ingenol 3-Angelate 98% | 5MG | $250 | 2026-05-27 | Buy |
| ACHEMBLOCK | V155991 | Ingenol 3-Angelate 98% | 10MG | $350 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0012-M005 | Ingenol-3-angelate ≥97%(HPLC) | 5mg | $350 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0012-M001 | Ingenol-3-angelate ≥97%(HPLC) | 1mg | $110 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0012-M005 | Ingenol-3-angelate ≥97%(HPLC) | 5mg | $420 | 2021-12-16 | Buy |
| AK Scientific | 3737AH | Ingenol3-angelate | 10mg | $977 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005276 | INGENOL 3-ANGELATE 95.00% | 1MG | $258.3 | 2021-12-16 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 10mM*1mLinDMSO(Solution) | $268 | 2026-05-25 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 10mM*1mLinDMSO(Solution) | $268 | 2026-05-26 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 5mg | $245 | 2026-05-25 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 5mg | $245 | 2026-05-26 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 10mM*1mLinDMSO(Solid+Solvent) | $255 | 2026-05-25 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 10mM*1mLinDMSO(Solid+Solvent) | $255 | 2026-05-26 | Buy |
| Arctom | AB2726 | Ingenol 3-Angelate 98%(HPLC) | 10mg | $312 | 2026-05-26 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 1mg | $77 | 2026-05-25 | Buy |
| Arctom | HY-B0719 | Ingenol Mebutate 99.65% | 1mg | $77 | 2026-05-26 | Buy |
Properties
Boiling point :576.9±50.0 °C(Predicted)
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :11.52±0.70(Predicted)
form :powder
color :white to beige
biological source :semisynthetic
Water Solubility :Soluble in 100% ethanol, DMSO, dichloromethane, and methanol. Insoluble in water.
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :VDJHFHXMUKFKET-WDUFCVPESA-N
SMILES :C(O[C@@H]1[C@@]2(O)[C@H](O)C(CO)=C[C@]3([H])C(=O)[C@]2(C=C1C)[C@H](C)C[C@@]1([H])C(C)(C)[C@]13[H])(=O)/C(/C)=C\C
Density :1.26±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO: soluble15mg/mL, clear
pka :11.52±0.70(Predicted)
form :powder
color :white to beige
biological source :semisynthetic
Water Solubility :Soluble in 100% ethanol, DMSO, dichloromethane, and methanol. Insoluble in water.
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :VDJHFHXMUKFKET-WDUFCVPESA-N
SMILES :C(O[C@@H]1[C@@]2(O)[C@H](O)C(CO)=C[C@]3([H])C(=O)[C@]2(C=C1C)[C@H](C)C[C@@]1([H])C(C)(C)[C@]13[H])(=O)/C(/C)=C\C
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||||||||||||||
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Description
Ingenol-3-angelate is a hydrophobic diterpene ester that can be isolated from the euphorb E. peplus. It rapidly induces cell death in proliferating keratinocytes through plasma membrane and mitochondrial disruption, although it can also initiate apoptosis in some cancer cell lines (LD90 = ~190 μM). Secondarily, ingenol-3-angelate causes inflammation due, at least in part, to activation of PKC, leading to antibody-dependent cellular cytotoxicity. These actions have relevance in diminishing actinic keratosis and, possibly, other cancers of the skin.More related product prices
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Suppliers and manufacturers
Shanghai Zheyan Biotech Co., Ltd.
Chengdu GLP biotechnology Co Ltd
Chengdu Biopurify Phytochemicals Ltd.
BOC Sciences
Wuhan ChemNorm Biotech Co.,Ltd.
Aktin Chemicals, Inc.
