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ChemicalBook >> CAS DataBase List >> Isotretinoin

Isotretinoin

Isotretinoin price.
  • $10 - $1767.15
  • Product name: Isotretinoin
  • CAS: 4759-48-2
  • MF: C20H28O2
  • MW: 300.44
  • EINECS:225-296-0
  • MDL Number:MFCD00079542
  • Synonyms:Tretinoin Impurity 1(Tretinoin EP Impurity A);Anti Acne Powerful Isotretinoin Powder Isotretinoin Pharmaceutical Raw Materials;Isotretinoin Capsules;Isotretinoin-D5/13-cis-Retinoic acid-D5;Roaccutan;(2Z,4E,6E,8E)-3,7-diMethyl-9-(2,6,6-triMethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid;A different diMension acid;Retinoin
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  • aablocks
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  • Adipogen Life Sciences
  • AK Scientific
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  • American Custom Chemicals Corporation
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Package
  • 10mg
  • 200mg
  • 3x100mg
  • 0.025kg
  • 0.05kg
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  • 10mM(in1mLDMSO)
  • 0.25kg
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  • 20 mg
  • i0800000
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  • 10mM(in 1mL DMSO)
  • 10g
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin ≥98%
  • Packaging100mg
  • Price$10
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin ≥98%
  • Packaging500mg
  • Price$11
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin ≥98%
  • Packaging1g
  • Price$12
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin 98%HPLC
  • Packaging5g
  • Price$27
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin 98%HPLC
  • Packaging10g
  • Price$46
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin ~75%(HPLC)
  • Packaging25g
  • Price$88
  • Updated2026-05-28
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  • Manufactureraablocks
  • Product numberAA003DSJ
  • Product descriptionIsotretinoin ~75%(HPLC)
  • Packaging100g
  • Price$220
  • Updated2026-05-28
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  • ManufacturerACHEMBLOCK
  • Product numberZ238325
  • Product descriptionIsotretinoin 98%
  • Packaging100G
  • Price$305
  • Updated2026-05-27
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3709-M250
  • Product descriptionIsotretinoin ≥98%
  • Packaging250mg
  • Price$80
  • Updated2026-05-06
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3709-M250
  • Product descriptionIsotretinoin ≥98%
  • Packaging250mg
  • Price$100
  • Updated2021-12-16
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  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3709-M050
  • Product descriptionIsotretinoin ≥98%
  • Packaging50mg
  • Price$25
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberAG-CR1-3709-M050
  • Product descriptionIsotretinoin ≥98%
  • Packaging50mg
  • Price$25
  • Updated2026-05-06
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10790
  • Product descriptionIsotretinoin >98%(HPLC),powder
  • Packaging25mg
  • Price$21
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product number0009TG
  • Product descriptionIsotretinoin, tech. ~75%(HPLC)
  • Packaging5g
  • Price$27
  • Updated2026-06-04
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  • ManufacturerAK Scientific
  • Product numberJ50160
  • Product descriptionIsotretinoin 95%
  • Packaging1g
  • Price$28
  • Updated2026-06-04
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10790
  • Product descriptionIsotretinoin >98%(HPLC),powder
  • Packaging100mg
  • Price$48
  • Updated2026-06-04
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
aablocks AA003DSJ Isotretinoin ≥98% 100mg $10 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin ≥98% 500mg $11 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin ≥98% 1g $12 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin 98%HPLC 5g $27 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin 98%HPLC 10g $46 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin ~75%(HPLC) 25g $88 2026-05-28 Buy
aablocks AA003DSJ Isotretinoin ~75%(HPLC) 100g $220 2026-05-28 Buy
ACHEMBLOCK Z238325 Isotretinoin 98% 100G $305 2026-05-27 Buy
Adipogen Life Sciences AG-CR1-3709-M250 Isotretinoin ≥98% 250mg $80 2026-05-06 Buy
Adipogen Life Sciences AG-CR1-3709-M250 Isotretinoin ≥98% 250mg $100 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3709-M050 Isotretinoin ≥98% 50mg $25 2021-12-16 Buy
Adipogen Life Sciences AG-CR1-3709-M050 Isotretinoin ≥98% 50mg $25 2026-05-06 Buy
AK Scientific J10790 Isotretinoin >98%(HPLC),powder 25mg $21 2026-06-04 Buy
AK Scientific 0009TG Isotretinoin, tech. ~75%(HPLC) 5g $27 2026-06-04 Buy
AK Scientific J50160 Isotretinoin 95% 1g $28 2026-06-04 Buy
AK Scientific J10790 Isotretinoin >98%(HPLC),powder 100mg $48 2026-06-04 Buy

Properties

Melting point :172-175 °C (lit.)
Boiling point :381.66°C (rough estimate)
Density :1.0597 (rough estimate)
refractive index :1.4800 (estimate)
storage temp. :-20°C
solubility :Practically insoluble in water, soluble in methylene chloride, slightly soluble in ethanol (96 per cent). It is sensitive to air, heat and light, especially in solution. Carry out all operations as rapidly as possible and avoid exposure to actinic light; use freshly prepared solutions.
pka :4.76±0.33(Predicted)
form :Fine Crystalline Powder
color :Yellow-orange to orange
biological source :synthetic
Water Solubility :insoluble
λmax :354nm(EtOH)(lit.)
Merck :14,5228
Stability :Stable, but probably air and light sensitive. Combustible. Incompatible with strong oxidizing agents.
Cosmetics Ingredients Functions :ANTI-SEBUM
InChI :1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)/b9-6+,12-11+,15-8+,16-14-
InChIKey :SHGAZHPCJJPHSC-YCNIQYBTSA-N
SMILES :[H]\C(C(O)=O)=C(C)\C=C\C=C(C)\C=C\C1=C(C)CCCC1(C)C
CAS DataBase Reference :4759-48-2(CAS DataBase Reference)
EPA Substance Registry System :Isotretinoin (4759-48-2)

Safety Information

Symbol(GHS): Exclamation Mark (GHS07)Health Hazard (GHS08)
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger
Precautionary statements:
P201 Obtain special instructions before use.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Isotretinoin is the 9-cis isomer of retinoic acid, a close relative of retinol, or vitamin A. It was originally developed to treat cystic acne, and today this is still its primary use despite several more modern applications of the drug, including a treatment for pancreatic and brain cancers. First shown to be an effective treatment for acne in 1982, its development stemmed from advances in knowledge of the effects of vitamin A to reduce or eliminate sebum production. Since that time, however, several instances of deleterious effects became well known, most notably birth defects arising from the use of isotretinoin.

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