KIRENOL
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- $49 - $2125
- Product name: KIRENOL
- CAS: 52659-56-0
- MF: C20H34O4
- MW: 338.49
- EINECS:
- MDL Number:MFCD00210519
- Synonyms:(1R,3S,4aS,4bS,7S,10aS)-1,2,3,4,4a,4b,5,6,7,9,10,10a-Dodecahydro-3-hydroxy-7-[(R)-1,2-dihydroxyethyl]-1,4a,7-trimethylphenanthrene-1-methanol;Kirenol;KIRENOL(P);Kirel;1,7-PhenanthrenediMethanol,1,2,3,4,4a,4b,5,6,7,- 9,10,10a-dodecahydro-3-hydroxy-R7- (hydroxyMethyl)-1,4a,7-triMethyl-,(R7R,1R,- 3S,4aS,4bR,7S,10aS)-;1,7-Phenanthrenedimethanol, 1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydro-3-hydroxy-α7-(hydroxymethyl)-1,4a,7-trimethyl-, (α7R,1R,3S,4aS,4bR,7S,10aS)-;(1R)-1-[(2S,4aR,4bS,6S,8R,8aS)-6-hydroxy-8-(hydroxymethyl)-2,4b,8-trimethyl-4,4a,5,6,7,8a,9,10-octahydro-3H-phenanthren-2-yl]ethane-1,2-diol;KirenolQ: What is Kirenol Q: What is the CAS Number of Kirenol Q: What is the storage condition of Kirenol Q: What are the applications of Kirenol
36 prices
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Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- Crysdot
- DC Chemicals
- JR MediChem
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberV1547
- Product descriptionKirenol
- Packaging250mg
- Price$988
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0016323
- Product descriptionKIRENOL 95.00%
- Packaging5MG
- Price$505.6
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberN1303
- Product descriptionKirenol
- Packaging20mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN98867
- Product descriptionKirenol ≥98%
- Packaging20mg
- Price$128
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY068911
- Product descriptionKirenol,98% ≥98%
- Packaging10mg
- Price$204.55
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1204
- Product descriptionKirenol
- Packaging5mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1204
- Product descriptionKirenol
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1204
- Product descriptionKirenol
- Packaging100mg
- Price$235
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number1204
- Product descriptionKirenol
- Packaging1g
- Price$1090
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546111
- Product descriptionKirenol >98%
- Packaging1mg
- Price$154.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb594061
- Product descriptionKirenol
- Packaging20mg
- Price$289
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546111
- Product descriptionKirenol >98%
- Packaging5mg
- Price$389.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb105307
- Product descriptionkirenol >98%,Standard References Grade
- Packaging20mg
- Price$569.5
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFK73795
- Product descriptionKirenol
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFK73795
- Product descriptionKirenol
- Packaging25mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFK73795
- Product descriptionKirenol
- Packaging50mg
- Price$204
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | V1547 | Kirenol | 250mg | $988 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0016323 | KIRENOL 95.00% | 5MG | $505.6 | 2021-12-16 | Buy |
| ApexBio Technology | N1303 | Kirenol | 20mg | $200 | 2021-12-16 | Buy |
| Arctom | CFN98867 | Kirenol ≥98% | 20mg | $128 | 2021-12-16 | Buy |
| Arctom | SY068911 | Kirenol,98% ≥98% | 10mg | $204.55 | 2021-12-16 | Buy |
| AvaChem | 1204 | Kirenol | 5mg | $49 | 2021-12-16 | Buy |
| AvaChem | 1204 | Kirenol | 10mg | $69 | 2021-12-16 | Buy |
| AvaChem | 1204 | Kirenol | 100mg | $235 | 2021-12-16 | Buy |
| AvaChem | 1204 | Kirenol | 1g | $1090 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546111 | Kirenol >98% | 1mg | $154.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb594061 | Kirenol | 20mg | $289 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546111 | Kirenol >98% | 5mg | $389.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb105307 | kirenol >98%,Standard References Grade | 20mg | $569.5 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FK73795 | Kirenol | 10mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FK73795 | Kirenol | 25mg | $120 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FK73795 | Kirenol | 50mg | $204 | 2021-12-16 | Buy |
Properties
Melting point :197.0 to 201.0 °C
Boiling point :516.9±35.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :14.06±0.20(Predicted)
color :White to Light Yellow
InChI :InChI=1/C20H34O4/c1-18(17(24)11-21)7-6-15-13(8-18)4-5-16-19(2,12-22)9-14(23)10-20(15,16)3/h8,14-17,21-24H,4-7,9-12H2,1-3H3/t14-,15-,16-,17+,18+,19+,20+/s3
InChIKey :NRYNTARIOIRWAB-QNOIMPALNA-N
SMILES :C[C@@]12C[C@H](O)C[C@@](C)(CO)[C@@]1([H])CCC1=C[C@@](C)([C@@H](O)CO)CC[C@@]21[H] |&1:1,3,6,10,16,18,24,r|
CAS DataBase Reference :52659-56-0
Boiling point :516.9±35.0 °C(Predicted)
Density :1.17±0.1 g/cm3(Predicted)
storage temp. :-20°C Freezer
solubility :Ethanol (Slightly), Methanol (Slightly)
form :Solid
pka :14.06±0.20(Predicted)
color :White to Light Yellow
InChI :InChI=1/C20H34O4/c1-18(17(24)11-21)7-6-15-13(8-18)4-5-16-19(2,12-22)9-14(23)10-20(15,16)3/h8,14-17,21-24H,4-7,9-12H2,1-3H3/t14-,15-,16-,17+,18+,19+,20+/s3
InChIKey :NRYNTARIOIRWAB-QNOIMPALNA-N
SMILES :C[C@@]12C[C@H](O)C[C@@](C)(CO)[C@@]1([H])CCC1=C[C@@](C)([C@@H](O)CO)CC[C@@]21[H] |&1:1,3,6,10,16,18,24,r|
CAS DataBase Reference :52659-56-0
Safety Information
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Description
Kirenol is a diterpenoid that has been found in S. orientalis and has diverse biological activities, including anti-arthritic and anti-inflammatory properties. It inhibits Gram-positive and Gram-negative bacterial growth in disc diffusion assays with MICs ranging from 39 to 156 and 312.5 to 625 μg/ml, respectively. Kirenol also reduces K652 chronic myeloid leukemia cell viability with a 48 hour IC50 value of 18.19 μg/ml and induces apoptosis. In vivo, kirenol (2 mg/kg, p.o.) reduces motor deficit, delays disease onset by approximately five days, and downregulates inflammatory CD4+IFN-γ+ Th1 cells and CD4+IL-17A+ Th17 cells in a mouse model of experimental autoimmune encephalomyelitis (EAE). Intragastric administration of kirenol (1-4 mg/kg) reduces the arthritis index, NF-kB activity, and paw swelling and increases annexin-1 expression without affecting glucocorticoid receptor α (GRα) expression in the synovium in a rat model of collagen-induced arthritis. Topical administration of kirenol (0.3-0.5% w/w) reduces edema induced by carrageenan, complete Freund''s adjuvant (CFA), and formalin in rats up to 44, 67, and 65%, respectively.More related product prices
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