Welcome to chemicalbook!

010-86108875

18162-48-6 872-50-4 Methylene Chloride naphthalene THF Titanium Dioxide

Structure Search

RFQ

Try our best to find the right business for you.

Messages

Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> KO-947

KO-947

$36 - $2700
Product name: KO-947
CAS: 1695533-89-1
MF: C21H17N5O
MW: 355.39
EINECS:
MDL Number:MFCD31657422
Synonyms:KO-947;6-benzyl-3-(pyridin-4-yl)-5,6-dihydro-1H-pyrazolo[4,3-g]quinazolin-7(8H)-one;KO947;KO-947;KO 947;7H-Pyrazolo[4,3-g]quinazolin-7-one, 1,5,6,8-tetrahydro-6-(phenylmethyl)-3-(4-pyridinyl)-;Inhibitor,ERK,KO-947,inhibit,KO 947,Extracellular signal regulated kinases,KO947;6-benzyl-3-(pyridin-4-yl)-1H,5H,6H,7H,8H-pyrazolo[4,3-g]quinazolin-7-one;KO-947 ，S8569

Price20 Properties Safety Information Description

20 prices

Selected condition：

Brand

aablocks
ACHEMBLOCK
AK Scientific
Cayman Chemical
ChemScene
DC Chemicals

Package

1mg
5mg
10mg
25mg
50mg
100mg
250mg
1g

Manufactureraablocks
Product numberAA01EO4K
Product descriptionKO-947 98
Packaging1mg
Price$56
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EO4K
Product descriptionKO-947 98+%
Packaging25mg
Price$98
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EO4K
Product descriptionKO-947 98+%
Packaging50mg
Price$166
Updated2026-05-30
Buy

Manufactureraablocks
Product numberAA01EO4K
Product descriptionKO-947 98+%
Packaging100mg
Price$279
Updated2026-05-30
Buy

ManufacturerACHEMBLOCK
Product numberY230223
Product descriptionKO-947 97%
Packaging100MG
Price$435
Updated2026-05-27
Buy

ManufacturerACHEMBLOCK
Product numberY230223
Product descriptionKO-947 97%
Packaging25MG
Price$145
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number8399EM
Product description6-Benzyl-3-pyridin-4-yl-5,8-dihydro-1H-pyrazolo[4,3-g]quinazolin-7-one
Packaging5mg
Price$252
Updated2021-12-16
Buy

ManufacturerAK Scientific
Product number8399EM
Product description6-Benzyl-3-pyridin-4-yl-5,8-dihydro-1H-pyrazolo[4,3-g]quinazolin-7-one
Packaging10mg
Price$370
Updated2021-12-16
Buy

ManufacturerCayman Chemical
Product number29213
Product descriptionKO947 ≥98%
Packaging25mg
Price$587
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number29213
Product descriptionKO947 ≥98%
Packaging10mg
Price$268
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number29213
Product descriptionKO947 ≥98%
Packaging5mg
Price$153
Updated2026-04-30
Buy

ManufacturerCayman Chemical
Product number29213
Product descriptionKO947 ≥98%
Packaging1mg
Price$36
Updated2026-04-30
Buy

ManufacturerChemScene
Product numberCS-0043627
Product descriptionKO-947 99.68%
Packaging5mg
Price$140
Updated2026-06-04
Buy

ManufacturerChemScene
Product numberCS-0043627
Product descriptionKO-947 99.68%
Packaging10mg
Price$224
Updated2026-06-04
Buy

ManufacturerChemScene
Product numberCS-0043627
Product descriptionKO-947 99.68%
Packaging50mg
Price$718
Updated2026-06-04
Buy

ManufacturerChemScene
Product numberCS-0043627
Product descriptionKO-947 99.68%
Packaging100mg
Price$1149
Updated2026-06-04
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA01EO4K	KO-947 98	1mg	$56	2026-05-30	Buy
aablocks	AA01EO4K	KO-947 98+%	25mg	$98	2026-05-30	Buy
aablocks	AA01EO4K	KO-947 98+%	50mg	$166	2026-05-30	Buy
aablocks	AA01EO4K	KO-947 98+%	100mg	$279	2026-05-30	Buy
ACHEMBLOCK	Y230223	KO-947 97%	100MG	$435	2026-05-27	Buy
ACHEMBLOCK	Y230223	KO-947 97%	25MG	$145	2026-05-27	Buy
AK Scientific	8399EM	6-Benzyl-3-pyridin-4-yl-5,8-dihydro-1H-pyrazolo[4,3-g]quinazolin-7-one	5mg	$252	2021-12-16	Buy
AK Scientific	8399EM	6-Benzyl-3-pyridin-4-yl-5,8-dihydro-1H-pyrazolo[4,3-g]quinazolin-7-one	10mg	$370	2021-12-16	Buy
Cayman Chemical	29213	KO947 ≥98%	25mg	$587	2026-04-30	Buy
Cayman Chemical	29213	KO947 ≥98%	10mg	$268	2026-04-30	Buy
Cayman Chemical	29213	KO947 ≥98%	5mg	$153	2026-04-30	Buy
Cayman Chemical	29213	KO947 ≥98%	1mg	$36	2026-04-30	Buy
ChemScene	CS-0043627	KO-947 99.68%	5mg	$140	2026-06-04	Buy
ChemScene	CS-0043627	KO-947 99.68%	10mg	$224	2026-06-04	Buy
ChemScene	CS-0043627	KO-947 99.68%	50mg	$718	2026-06-04	Buy
ChemScene	CS-0043627	KO-947 99.68%	100mg	$1149	2026-06-04	Buy

Next Last

Properties

Boiling point :704.1±60.0 °C(Predicted)
Density :1.354±0.06 g/cm3(Predicted)
storage temp. :4°C, protect from light
solubility :DMSO:66.75(Max Conc. mg/mL);187.82(Max Conc. mM)
form :A crystalline solid
pka :13.32±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H302	Harmful if swallowed	Acute toxicity,oral	Category 4	Warning	P264, P270, P301+P312, P330, P501
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312	IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

KO947 is an ERK inhibitor (IC₅₀ = <50 nM for ERK2). It is greater than 50-fold selective for ERK over a panel of 450 kinases. KO947 reduces phosphorylation of the ERK target p90 ribosomal S6 kinase (RSK) in A375 cancer cells containing constitutively active B-RAF^V600E with an IC₅₀ value of less than 250 nM. It inhibits proliferation of A375 cells, as well as mutant K-Ras-expressing HCT116 and H358 cancer cell lines (IC₅₀s = 50-250 nM for all).

More related product prices

LY3214996 CAY10561 AZD0364 Sitagliptin

Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. BOC Sciences Nanjing Norris-Pharm Technology Co., Ltd HangZhou YuHao Chemical Technology Co., Ltd. Shanghai Lollane Biological Technology Co.,Ltd. YouCoChem (Beijing) Chemical Technology Co., Ltd. Shanghaizehan biopharma technology co., Ltd. Shanghai YuanYe Biotechnology Co., Ltd. ShangHai Biochempartner Co.,Ltd Shanghai Rechem science Co., Ltd.

HomePage | About Us | Member Companies | Advertising | Contact us | Previous WebSite | MSDS | CAS Index | CAS DataBase | Product Catalog | Links | Privacy | Terms | Product Manufacturers | New Products
All products displayed on this website are only for non-medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.
According to relevant laws and regulations and the regulations of this website, units or individuals who purchase hazardous materials should obtain valid qualifications and qualification conditions.

KO-947

Properties

Safety Information

Description

Related product price

Suppliers and manufacturers