KU-0063794
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- $50 - $2839
- Product name: KU-0063794
- CAS: 938440-64-3
- MF: C25H31N5O4
- MW: 465.54
- EINECS:
- MDL Number:MFCD11977741
- Synonyms:BENZENEMETHANOL, 5-[2-[(2R,6S)-2,6-DIMETHYL-4-MORPHOLINYL]-4-(4-MORPHOLINYL)PYRIDO[2,3-D]PYRIMIDIN-7-YL]-2-METHOXY-, REL-;KU0063794;5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;(5-(2-((2R,6S)-2,6-Dimethylmorpholino)-4-morpholinopyrido[2,3-d]pyrimidin-7-yl)-2-methoxyphenyl)methanol;rel-5-[2-[(2R,6S)-2,6-dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol;KU0063794(KU63794);KU-0063794(KU 0063794);CS-28
61 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 2mg
- 10.00mg
- 20mg
- 10
- 50.00mg
- 100.00mg
- 250mg
- 1g
- 1mg
- 10mM(in 1mL DMSO)
- 5mg
- 10mg
- 25mg
- 100mg
- 10mM(in1mLDMSO)
- 50mg
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M001
- Product descriptionKU-0063794 ≥95%
- Packaging1mg
- Price$76
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M005
- Product descriptionKU-0063794 ≥95%
- Packaging5mg
- Price$97
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M010
- Product descriptionKU-0063794 ≥95%
- Packaging10mg
- Price$162
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M050
- Product descriptionKU-0063794 ≥95%
- Packaging50mg
- Price$486
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M100
- Product descriptionKU-0063794 ≥95%
- Packaging100mg
- Price$702
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M010
- Product descriptionKU 0063794 ≥95%
- Packaging10mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1050-M001
- Product descriptionKU 0063794 ≥95%
- Packaging1mg
- Price$76
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1050
- Product descriptionKU 0063794
- Packaging5mg
- Price$110
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN1050
- Product descriptionKU 0063794
- Packaging50mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000836
- Product descriptionKU 0063794 95.00%
- Packaging1MG
- Price$228.9
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000836
- Product descriptionKU 0063794 95.00%
- Packaging10MG
- Price$750.75
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberKIN0000836
- Product descriptionKU 0063794 95.00%
- Packaging50MG
- Price$1155
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5078
- Product descriptionKU-0063794
- Packaging100mg
- Price$480
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA5078
- Product descriptionKU 0063794
- Packaging100mg
- Price$480
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5078
- Product descriptionKU 0063794
- Packaging25mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA5078
- Product descriptionKU-0063794
- Packaging25mg
- Price$150
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | SYN-1050-M001 | KU-0063794 ≥95% | 1mg | $76 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M005 | KU-0063794 ≥95% | 5mg | $97 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M010 | KU-0063794 ≥95% | 10mg | $162 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M050 | KU-0063794 ≥95% | 50mg | $486 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M100 | KU-0063794 ≥95% | 100mg | $702 | 2026-05-06 | Buy |
| Adipogen Life Sciences | SYN-1050-M010 | KU 0063794 ≥95% | 10mg | $162 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1050-M001 | KU 0063794 ≥95% | 1mg | $76 | 2021-12-16 | Buy |
| AK Scientific | SYN1050 | KU 0063794 | 5mg | $110 | 2021-12-16 | Buy |
| AK Scientific | SYN1050 | KU 0063794 | 50mg | $470 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000836 | KU 0063794 95.00% | 1MG | $228.9 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000836 | KU 0063794 95.00% | 10MG | $750.75 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | KIN0000836 | KU 0063794 95.00% | 50MG | $1155 | 2021-12-16 | Buy |
| ApexBio Technology | A5078 | KU-0063794 | 100mg | $480 | 2026-05-06 | Buy |
| ApexBio Technology | A5078 | KU 0063794 | 100mg | $480 | 2021-12-16 | Buy |
| ApexBio Technology | A5078 | KU 0063794 | 25mg | $150 | 2021-12-16 | Buy |
| ApexBio Technology | A5078 | KU-0063794 | 25mg | $150 | 2026-05-06 | Buy |
Properties
Boiling point :694.3±65.0 °C(Predicted)
Density :1.248
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :14.20±0.10(Predicted)
form :powder
color :white to beige
InChIKey :RFSMUFRPPYDYRD-CALCHBBNSA-N
SMILES :COc1ccc(cc1CO)-c2ccc3c(nc(nc3n2)N4C[C@H](C)O[C@H](C)C4)N5CCOCC5
Density :1.248
storage temp. :2-8°C
solubility :DMSO: >2mg/mL (warmed)
pka :14.20±0.10(Predicted)
form :powder
color :white to beige
InChIKey :RFSMUFRPPYDYRD-CALCHBBNSA-N
SMILES :COc1ccc(cc1CO)-c2ccc3c(nc(nc3n2)N4C[C@H](C)O[C@H](C)C4)N5CCOCC5
Safety Information
| Symbol(GHS): |
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| Signal word: | Danger | ||||||||||||||||
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Description
The mammalian target of rapamycin (mTOR) is a serine-threonine kinase which acts as part of two distinct complexes, TORC1 and TORC2. Both complexes (TORC1/2) play central roles in cell growth, gene expression, angiogenesis, and cell survival. Ku-0063794 is a cell-permeable, selective dual inhibitor of mTORC1 and mTORC2 (IC50 = 10 nM). It does not affect the activity of 76 other protein kinases or seven lipid kinases, including PI3Ks. Ku-0063794 inhibits cell growth by inducing G1-cell cycle arrest and autophagy, but not apoptosis, and inhibits tumor growth in a xenograft model of renal cell carcinoma (8 mg/kg for 46 days).More related product prices
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