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ChemicalBook >> CAS DataBase List >> LY3039478

LY3039478

$41 - $6650
Product name: LY3039478
CAS: 1421438-81-4
MF: C22H23F3N4O4
MW: 464.44
EINECS:
MDL Number:MFCD26142650
Synonyms:4-trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6;LY3039478; LY 3039478; LY-3039478; CRENIGACESTAT;LY3039478;4,4,4-Trifluoro-N-((S)-1-(((S)-5-(2-hydroxyethyl)-6-oxo-6,7-dihydro-5H-benzo[d]pyrido[2,3-b]azepin-7-yl)amino)-1-oxopropan-2-yl)butanamide;N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide;Butanamide, N-[(1S)-2-[[(7S)-6,7-dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluoro-;CRENIGACESTAT (LY3039478);LY3039478(Crenigacestat)

Price37 Properties Safety Information Description

37 prices

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Brand

aablocks
ACHEMBLOCK
AK Scientific
ApexBio Technology
Arctom
Biosynth
Cayman Chemical
ChemScene
Crysdot
DC Chemicals
TRC

Package

10mM(1mLinDMSO)
1mg
2mg
5mg
10mg
25mg
50mg
100MG
250mg
1g

Manufactureraablocks
Product numberAA001HRR
Product descriptionN-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%
Packaging1mg
Price$42
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001HRR
Product descriptionN-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%
Packaging2mg
Price$73
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001HRR
Product descriptionN-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%
Packaging5mg
Price$88
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001HRR
Product descriptionN-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%
Packaging10mg
Price$145
Updated2026-05-28
Buy

Manufactureraablocks
Product numberAA001HRR
Product descriptionN-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%
Packaging25mg
Price$261
Updated2026-05-28
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ManufacturerACHEMBLOCK
Product numberI-9796
Product descriptionLY3039478 98%
Packaging25MG
Price$266
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberI-9796
Product descriptionLY3039478 98%
Packaging100MG
Price$945
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberI-9796
Product descriptionLY3039478 98%
Packaging5MG
Price$86
Updated2026-05-27
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ManufacturerACHEMBLOCK
Product numberI-9796
Product descriptionLY3039478 98%
Packaging2MG
Price$41
Updated2026-05-27
Buy

ManufacturerAK Scientific
Product number2689DU
Product descriptionCrenigacestat
Packaging5mg
Price$324
Updated2021-12-16
Buy

ManufacturerApexBio Technology
Product numberA4023
Product descriptionLY3039478
Packaging5mg
Price$124
Updated2026-05-06
Buy

ManufacturerArctom
Product numberSLK-S7169
Product descriptionCrenigacestat (LY3039478) 99.89%
Packaging5mg
Price$162
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S7169
Product descriptionCrenigacestat (LY3039478) 99.89%
Packaging10mM(1mLinDMSO)
Price$247
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S7169
Product descriptionCrenigacestat (LY3039478) 99.89%
Packaging25mg
Price$542
Updated2026-05-26
Buy

ManufacturerArctom
Product numberSLK-S7169
Product descriptionCrenigacestat (LY3039478) 99.89%
Packaging1g
Price$6650
Updated2026-05-26
Buy

ManufacturerBiosynth
Product numberFT76166
Product descriptionLY3039478
Packaging2mg
Price$300
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
aablocks	AA001HRR	N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%	1mg	$42	2026-05-28	Buy
aablocks	AA001HRR	N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%	2mg	$73	2026-05-28	Buy
aablocks	AA001HRR	N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%	5mg	$88	2026-05-28	Buy
aablocks	AA001HRR	N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%	10mg	$145	2026-05-28	Buy
aablocks	AA001HRR	N-[(1S)-2-[[(7S)-6,7-Dihydro-5-(2-hydroxyethyl)-6-oxo-5H-pyrido[3,2-a][3]benzazepin-7-yl]amino]-1-methyl-2-oxoethyl]-4,4,4-trifluorobutanamide 95%	25mg	$261	2026-05-28	Buy
ACHEMBLOCK	I-9796	LY3039478 98%	25MG	$266	2026-05-27	Buy
ACHEMBLOCK	I-9796	LY3039478 98%	100MG	$945	2026-05-27	Buy
ACHEMBLOCK	I-9796	LY3039478 98%	5MG	$86	2026-05-27	Buy
ACHEMBLOCK	I-9796	LY3039478 98%	2MG	$41	2026-05-27	Buy
AK Scientific	2689DU	Crenigacestat	5mg	$324	2021-12-16	Buy
ApexBio Technology	A4023	LY3039478	5mg	$124	2026-05-06	Buy
Arctom	SLK-S7169	Crenigacestat (LY3039478) 99.89%	5mg	$162	2026-05-26	Buy
Arctom	SLK-S7169	Crenigacestat (LY3039478) 99.89%	10mM(1mLinDMSO)	$247	2026-05-26	Buy
Arctom	SLK-S7169	Crenigacestat (LY3039478) 99.89%	25mg	$542	2026-05-26	Buy
Arctom	SLK-S7169	Crenigacestat (LY3039478) 99.89%	1g	$6650	2026-05-26	Buy
Biosynth	FT76166	LY3039478	2mg	$300	2021-12-16	Buy

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Properties

Boiling point :818.7±65.0 °C(Predicted)
Density :1.41±0.1 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :≥23.2 mg/mL in DMSO; insoluble in H2O; ≥89.4 mg/mL in EtOH with ultrasonic
form :solid
pka :12.75±0.20(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):

Signal word:

Warning

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	P-Codes
H315	Causes skin irritation	Skin corrosion/irritation	Category 2	Warning	P264, P280, P302+P352, P321,P332+P313, P362
H319	Causes serious eye irritation	Serious eye damage/eye irritation	Category 2A	Warning	P264, P280, P305+P351+P338,P337+P313P
H335	May cause respiratory irritation	Specific target organ toxicity, single exposure;Respiratory tract irritation	Category 3	Warning

Precautionary statements:

P261	Avoid breathing dust/fume/gas/mist/vapours/spray.
P264	Wash hands thoroughly after handling.
P264	Wash skin thouroughly after handling.
P271	Use only outdoors or in a well-ventilated area.
P280	Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352	IF ON SKIN: wash with plenty of soap and water.
P304+P340	IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338	IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312	Call a POISON CENTER or doctor/physician if you feel unwell.
P321	Specific treatment (see … on this label).
P332+P313	IF SKIN irritation occurs: Get medical advice/attention.
P337+P313	IF eye irritation persists: Get medical advice/attention.
P362	Take off contaminated clothing and wash before reuse.
P403+P233	Store in a well-ventilated place. Keep container tightly closed.
P405	Store locked up.
P501	Dispose of contents/container to..…

Description

LY 3039478 is used in the preparation of medicaments for combination antitumor therapy with Notch and PD-1 or PD-Li inhibitors.

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Suppliers and manufacturers

Shanghai Boyle Chemical Co., Ltd. WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. Jinan Trio PharmaTech Co., Ltd. BOC Sciences Dalian Meilun Biotech Co., Ltd. ShangHai Caerulum Pharma Discovery Co., Ltd. Bide Pharmatech Ltd. AdooQ Bioscience CHINA Shanghai Lollane Biological Technology Co.,Ltd. Twochem Co.Ltd

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LY3039478

Properties

Safety Information

Description

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