Lonidamine
|
- $10 - $1872
- Product name: Lonidamine
- CAS: 50264-69-2
- MF: C15H10Cl2N2O2
- MW: 321.16
- EINECS:256-510-0
- MDL Number:MFCD00866285
- Synonyms:af1890 ;lonidamin;1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid;1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)Methyl]-;1-(2,4-dichlorbenzyl)-indazole-3-carboxylicacid ;1-(2,4-dichlorobenzyl)-1h-indazole-3-carboxylicaci ;Lonidamine (AF1890);Lonidamine, 99%, mitochondrial hexokinase inhibitor
75 prices
Selected condition：
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- Tocris
- Usbiological
Package
- 5mg
- 10mM*1mLinDMSO(Solution)
- 25mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 10mM(1mLinDMSO)
- 50
- 10mg
- 10mM*1mLinDMSO
- 10
- 50mg
- 100mg
- 10mM(in1mLDMSO)
- 250mg
- 500mg
- 5g
- EvaluationSample
- 1g
- Manufactureraablocks
- Product numberAA0037AT
- Product description1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid ≥99%
- Packaging25mg
- Price$21
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037AT
- Product description1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95%
- Packaging100mg
- Price$55
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037AT
- Product description1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95%
- Packaging250mg
- Price$65
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037AT
- Product description1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95%
- Packaging1g
- Price$198
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA0037AT
- Product description1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95%
- Packaging5g
- Price$596
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16052
- Product descriptionLonidamine 99%
- Packaging5G
- Price$665
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16052
- Product descriptionLonidamine 99%
- Packaging1G
- Price$200
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberR16052
- Product descriptionLonidamine 99%
- Packaging250MG
- Price$90
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberC483
- Product descriptionLonidamine
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- Packaging5mg
- Price$51
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB1964
- Product descriptionLonidamine
- PackagingEvaluationSample
- Price$30
- Updated2026-05-06
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging100mg
- Price$48
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging50mg
- Price$26
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging5mg
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS526212
- Product description1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99%
- Packaging10mg
- Price$13
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA0037AT | 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid ≥99% | 25mg | $21 | 2026-05-28 | Buy |
| aablocks | AA0037AT | 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95% | 100mg | $55 | 2026-05-28 | Buy |
| aablocks | AA0037AT | 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95% | 250mg | $65 | 2026-05-28 | Buy |
| aablocks | AA0037AT | 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95% | 1g | $198 | 2026-05-28 | Buy |
| aablocks | AA0037AT | 1-(2,4-Dichlorobenzyl)-1H-Indazole-3-Carboxylic Acid 95% | 5g | $596 | 2026-05-28 | Buy |
| ACHEMBLOCK | R16052 | Lonidamine 99% | 5G | $665 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16052 | Lonidamine 99% | 1G | $200 | 2026-05-27 | Buy |
| ACHEMBLOCK | R16052 | Lonidamine 99% | 250MG | $90 | 2026-05-27 | Buy |
| AK Scientific | C483 | Lonidamine | 25mg | $94 | 2021-12-16 | Buy |
| ApexBio Technology | B1964 | Lonidamine | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B1964 | Lonidamine | 5mg | $51 | 2026-05-06 | Buy |
| ApexBio Technology | B1964 | Lonidamine | EvaluationSample | $30 | 2026-05-06 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 100mg | $48 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 50mg | $26 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 5mg | $10 | 2021-12-16 | Buy |
| Arctom | AS526212 | 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylicacid ≥99% | 10mg | $13 | 2021-12-16 | Buy |
Properties
Melting point :207-209°C
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
pka :3.00±0.10(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
SMILES :N1(CC2=CC=C(Cl)C=C2Cl)C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Boiling point :537.9±45.0 °C(Predicted)
Density :1.4835 (rough estimate)
refractive index :1.6070 (estimate)
storage temp. :Sealed in dry,2-8°C
solubility :Soluble in DMSO (up to 25 mg/ml).
pka :3.00±0.10(Predicted)
form :solid
color :White
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month.
InChI :InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
InChIKey :WDRYRZXSPDWGEB-UHFFFAOYSA-N
SMILES :N1(CC2=CC=C(Cl)C=C2Cl)C2=C(C=CC=C2)C(C(O)=O)=N1
CAS DataBase Reference :50264-69-2(CAS DataBase Reference)
Safety Information
| Symbol(GHS): |
 
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| Signal word: | Danger | ||||||||||||||||||||||||||||
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Description
Lonidamine is a derivative of indazole-3-carboxylic acid. It is a kind of orally administrated small molecule, which can inhibit the glycolysis process through inactivating the hexokinase (the first step in glycolysis). It has been shown that cancer cell primarily generates energy through glycolysis process. Therefore, Lonidamine has been used for the treatment of several kinds of cancers. One special property of Lonidamine is that it seems to enhance aerobic glycolysis in normal cells, but inhibit glycolysis only in cancer cells. In addition, there are also evidences that Lonidamine may increase the occurrence of apoptosis. It has also been shown that Lonidamine is effective in the treatment of benigh prostatic hyperplasia (BPH).Related product price
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