MIBEFRADIL
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- $72 - $2700
- Product name: MIBEFRADIL
- CAS: 116666-63-8
- MF: C29H40Cl2FN3O3
- MW: 568.5506032
- EINECS:
- MDL Number:MFCD11044451
- Synonyms:CS-1455;Mibefradil 2Hcl(Ro 40-5967);(1s-cis)-orid ;2-(2-((3-(1h-benzimidazol-2-yl)propyl)methylamino)ethyl)-aceticaci ;6-fluoro-1,2,3,4-tetrahydro-1-(1-methylethyl)-2-naphthalenylester,dihydrochl ;ro40-5967/001 ;Mibefradil hydrate dihydrochloride;Ro 40-5967 hydrate, (1S,2S)-2-[2[[3-(2-Benzimidazolylpropyl]methylamino]ethyl]-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate hydrate dihydrochloride
25 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Cayman Chemical
- Chemenu
- ChemScene
- DC Chemicals
- Sigma-Aldrich
- TRC
Package
- 5mg
- 10mg
- 25MG
- 50mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product number3848AH
- Product descriptionMibefradildihydrochloride
- Packaging50mg
- Price$818
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number3848AH
- Product descriptionMibefradildihydrochloride
- Packaging250mg
- Price$1609
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186181
- Product descriptionMibefradildihydrochloride 97%
- Packaging5mg
- Price$73
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186181
- Product descriptionMibefradildihydrochloride 97%
- Packaging10mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA186181
- Product descriptionMibefradildihydrochloride 97%
- Packaging50mg
- Price$227
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCBL0000334
- Product descriptionMIBEFRADIL DIHYDROCHLORIDE HYDRATE 95.00%
- Packaging5MG
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCBL0000334
- Product descriptionMIBEFRADIL DIHYDROCHLORIDE HYDRATE 95.00%
- Packaging25MG
- Price$966.57
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3605
- Product descriptionMibefradildihydrochloride
- Packaging5mg
- Price$134
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3605
- Product descriptionMibefradildihydrochloride
- Packaging10mg
- Price$223
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA3605
- Product descriptionMibefradildihydrochloride
- Packaging50mg
- Price$979
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS469338
- Product descriptionMibefradildihydrochloride 97%
- Packaging5mg
- Price$72
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS469338
- Product descriptionMibefradildihydrochloride 97%
- Packaging10mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number15037
- Product descriptionMibefradil (hydrochloride) ≥95%
- Packaging5mg
- Price$106
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15037
- Product descriptionMibefradil (hydrochloride) ≥95%
- Packaging10mg
- Price$187
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15037
- Product descriptionMibefradil (hydrochloride) ≥95%
- Packaging25mg
- Price$440
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number15037
- Product descriptionMibefradil (hydrochloride) ≥95%
- Packaging50mg
- Price$826
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 3848AH | Mibefradildihydrochloride | 50mg | $818 | 2021-12-16 | Buy |
| AK Scientific | 3848AH | Mibefradildihydrochloride | 250mg | $1609 | 2021-12-16 | Buy |
| Ambeed | A186181 | Mibefradildihydrochloride 97% | 5mg | $73 | 2021-12-16 | Buy |
| Ambeed | A186181 | Mibefradildihydrochloride 97% | 10mg | $134 | 2021-12-16 | Buy |
| Ambeed | A186181 | Mibefradildihydrochloride 97% | 50mg | $227 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CBL0000334 | MIBEFRADIL DIHYDROCHLORIDE HYDRATE 95.00% | 5MG | $550 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CBL0000334 | MIBEFRADIL DIHYDROCHLORIDE HYDRATE 95.00% | 25MG | $966.57 | 2021-12-16 | Buy |
| ApexBio Technology | A3605 | Mibefradildihydrochloride | 5mg | $134 | 2021-12-16 | Buy |
| ApexBio Technology | A3605 | Mibefradildihydrochloride | 10mg | $223 | 2021-12-16 | Buy |
| ApexBio Technology | A3605 | Mibefradildihydrochloride | 50mg | $979 | 2021-12-16 | Buy |
| Arctom | AS469338 | Mibefradildihydrochloride 97% | 5mg | $72 | 2021-12-16 | Buy |
| Arctom | AS469338 | Mibefradildihydrochloride 97% | 10mg | $133 | 2021-12-16 | Buy |
| Cayman Chemical | 15037 | Mibefradil (hydrochloride) ≥95% | 5mg | $106 | 2024-03-01 | Buy |
| Cayman Chemical | 15037 | Mibefradil (hydrochloride) ≥95% | 10mg | $187 | 2024-03-01 | Buy |
| Cayman Chemical | 15037 | Mibefradil (hydrochloride) ≥95% | 25mg | $440 | 2024-03-01 | Buy |
| Cayman Chemical | 15037 | Mibefradil (hydrochloride) ≥95% | 50mg | $826 | 2024-03-01 | Buy |
Properties
Melting point :128℃
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :H2O: 24 mg/mL, soluble
pka :4.8; 5.5(at 25℃)
form :solid
color :white
Water Solubility :H2O: soluble >20mg/mL
absolute ethanol: insoluble Stability :Hygroscopic
InChIKey :IZSWBBGKLWFDOC-YKXHUFBBSA-N
SMILES :O.Cl.Cl.COCC(=O)O[C@]3(CCN(C)CCCc1nc2ccccc2[nH]1)CCc4cc(F)ccc4[C@@H]3C(C)C
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :H2O: 24 mg/mL, soluble
pka :4.8; 5.5(at 25℃)
form :solid
color :white
Water Solubility :H2O: soluble >20mg/mL
absolute ethanol: insoluble Stability :Hygroscopic
InChIKey :IZSWBBGKLWFDOC-YKXHUFBBSA-N
SMILES :O.Cl.Cl.COCC(=O)O[C@]3(CCN(C)CCCc1nc2ccccc2[nH]1)CCc4cc(F)ccc4[C@@H]3C(C)C
Safety Information
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| Signal word: | Warning | ||||||||||||||
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Description
Mibefradil is a general calcium channel blocker that shows modest selectivity for T-type channels over L-type channels (IC50 = 2.7 and 18.6 μM, respectively). It is a potent vasodilator, increasing coronary artery flow with an EC50 value of 54 nM. Mibefradil has minimal negative inotropic effects, supporting its use as an anti-hypertensive agent.Related product price
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