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ChemicalBook >> CAS DataBase List >> Methyl trifluoroacetate

Methyl trifluoroacetate

Methyl trifluoroacetate price.
  • $10 - $6454.37
  • Product name: Methyl trifluoroacetate
  • CAS: 431-47-0
  • MF: C3H3F3O2
  • MW: 128.05
  • EINECS:207-074-5
  • MDL Number:MFCD00000417
  • Synonyms:Methyl trifluoroacet;Methyl trifluoroacetate, 99% 25ML;METHYL TRIFLUOROACETATE FOR SYNTHESIS;Trifluoroacetic acid methyl ester, Methyl 2,2,2-trifluoroethanoate;Methyl trifluoroacetate (TFAM);Methyletrifluoroacetate;METHYL TRIFLUOROACETATE;Acetic acid, trifluoro-, methyl ester
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  • AHH
  • AK Scientific
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Package
  • 5g
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  • ManufacturerAHH
  • Product numberMT-19031
  • Product descriptionMethyl Trifluoroacetate 98%
  • Packaging1000g
  • Price$600
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-19031
  • Product descriptionMethyl trifluoroacetate 97%
  • Packaging1000g
  • Price$600
  • Updated2026-05-25
  • Buy
  • ManufacturerAK Scientific
  • Product number7014AF
  • Product descriptionMethyl Trifluoroacetate
  • Packaging25g
  • Price$71
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0026565
  • Product descriptionMETHYL TRIFLUOROACETATE 95.00%
  • Packaging1KG
  • Price$6454.37
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM334256
  • Product descriptionmethyl2,2,2-trifluoroacetate 98%
  • Packaging1000g
  • Price$83
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging5KG
  • Price$1150.12
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyltrifluoroacetate,99%(GC) 99%(GC)
  • Packaging500G
  • Price$137.76
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging500G
  • Price$172.36
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging1KG
  • Price$256.48
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging25G
  • Price$19.73
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging250G
  • Price$90.84
  • Updated2026-05-19
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyltrifluoroacetate,≥99%(GC)Hazmat ≥99%(GC)
  • Packaging25G
  • Price$15.6
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyltrifluoroacetate,≥99%(GC)Hazmat ≥99%(GC)
  • Packaging100G
  • Price$31.2
  • Updated2021-12-16
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  • ManufacturerChem-Impex
  • Product number42373
  • Product descriptionMethyl trifluoroacetate ≥99%(GC)
  • Packaging100G
  • Price$41.96
  • Updated2026-05-19
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  • ManufacturerFrontier Specialty Chemicals
  • Product numberJK421428
  • Product descriptionMethyl Trifluoroacetate 99%
  • Packaging25g
  • Price$51
  • Updated2021-12-16
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  • ManufacturerFrontier Specialty Chemicals
  • Product numberJK421428
  • Product descriptionMethyl Trifluoroacetate 99%
  • Packaging100g
  • Price$142
  • Updated2021-12-16
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Manufacturer Product number Product description Packaging Price Updated Buy
AHH MT-19031 Methyl Trifluoroacetate 98% 1000g $600 2021-12-16 Buy
AHH MT-19031 Methyl trifluoroacetate 97% 1000g $600 2026-05-25 Buy
AK Scientific 7014AF Methyl Trifluoroacetate 25g $71 2021-12-16 Buy
American Custom Chemicals Corporation HCH0026565 METHYL TRIFLUOROACETATE 95.00% 1KG $6454.37 2021-12-16 Buy
Chemenu CM334256 methyl2,2,2-trifluoroacetate 98% 1000g $83 2021-12-16 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 5KG $1150.12 2026-05-19 Buy
Chem-Impex 42373 Methyltrifluoroacetate,99%(GC) 99%(GC) 500G $137.76 2021-12-16 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 500G $172.36 2026-05-19 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 1KG $256.48 2026-05-19 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 25G $19.73 2026-05-19 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 250G $90.84 2026-05-19 Buy
Chem-Impex 42373 Methyltrifluoroacetate,≥99%(GC)Hazmat ≥99%(GC) 25G $15.6 2021-12-16 Buy
Chem-Impex 42373 Methyltrifluoroacetate,≥99%(GC)Hazmat ≥99%(GC) 100G $31.2 2021-12-16 Buy
Chem-Impex 42373 Methyl trifluoroacetate ≥99%(GC) 100G $41.96 2026-05-19 Buy
Frontier Specialty Chemicals JK421428 Methyl Trifluoroacetate 99% 25g $51 2021-12-16 Buy
Frontier Specialty Chemicals JK421428 Methyl Trifluoroacetate 99% 100g $142 2021-12-16 Buy

Properties

Melting point :-78 °C
Boiling point :43-43.5 °C (lit.)
Density :1.273 g/mL at 25 °C (lit.)
vapor pressure :5.77 psi ( 20 °C)
refractive index :n20/D 1.291(lit.)
Flash point :19 °F
storage temp. :Inert atmosphere,2-8°C
solubility :8g/l
form :Liquid
color :Clear colorless
Specific Gravity :1.273
PH :7 (8g/l, H2O, 20℃)
explosive limit :6.1-24.8%(V)
Water Solubility :8 g/L
Sensitive :Moisture Sensitive
BRN :1756070
Henry's Law Constant :1.1×10-3 mol/(m3Pa) at 25℃, Burkholder et al. (2019)
Dielectric constant :11.460000000000001
Stability :Volatile
InChI :1S/C3H3F3O2/c1-8-2(7)3(4,5)6/h1H3
InChIKey :VMVNZNXAVJHNDJ-UHFFFAOYSA-N
SMILES :COC(=O)C(F)(F)F
LogP :0.6
CAS DataBase Reference :431-47-0(CAS DataBase Reference)
NIST Chemistry Reference :CF3C(O)OCH3(431-47-0)
EPA Substance Registry System :Acetic acid, trifluoro-, methyl ester (431-47-0)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Useful reagent for trifluoroacetylation of amines under mild conditions. In the presence of 1,1,3,3-Tetramethyl-guanidine, has also been used for the N-acylation of amino acids. It is used as an intermediate in the synthesis of pharmaceutical and agricultural chemicals. The chemical reactions usually involve nucleophilic substitution of the ester and are useful for the preparation of trifluoroacylated compounds.

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