Mizolastine
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- $21 - $1841
- Product name: Mizolastine
- CAS: 108612-45-9
- MF: C24H25FN6O
- MW: 432.49
- EINECS:1308068-626-2
- MDL Number:MFCD23140913
- Synonyms:4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p ;iperidinyl)methylamino)- ;2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one;MIZOLASTINE;2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone;Mizolastine HCl;2-[[1-[1-(4-fluorobenzyl)benzimidazol-2-yl]-4-piperidyl]-methyl-amino]-1H-pyrimidin-6-one;2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1H-pyrimidin-6-one
69 prices
Selected condition：
Brand
- aablocks
- AHH
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- AvaChem
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TCI Chemical
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 25mg
- 50mg
- 0.1g
- 100mg
- 10mM(in1mLDMSO)
- 200mg
- 250mg
- 500mg
- 1g
- 5g
- 25g
- 100g
- 10 mg
- Manufactureraablocks
- Product numberAA007C3L
- Product description2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98%
- Packaging200mg
- Price$27
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007C3L
- Product description2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98%
- Packaging1g
- Price$56
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007C3L
- Product description2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98%
- Packaging5g
- Price$200
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007C3L
- Product description2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone 98%
- Packaging25g
- Price$807
- Updated2026-05-28
- Buy
- ManufacturerAHH
- Product numberAPI-1754
- Product descriptionMizolastine 98%
- Packaging0.1g
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerAHH
- Product numberAPI-1754
- Product descriptionMizolastine 97%
- Packaging0.1g
- Price$370
- Updated2026-05-26
- Buy
- ManufacturerAK Scientific
- Product numberI520
- Product descriptionMizolastine 98%
- Packaging5g
- Price$241
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98981
- Product descriptionMizolastine 95%
- Packaging5g
- Price$180
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10320
- Product descriptionMizolastine >98%,powder
- Packaging100mg
- Price$95
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98981
- Product descriptionMizolastine
- Packaging1g
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ10320
- Product descriptionMizolastine >98%,powder
- Packaging5mg
- Price$22
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ98981
- Product descriptionMizolastine 95%
- Packaging1g
- Price$46
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberJ10320
- Product descriptionMizolastine >98%,powder
- Packaging25mg
- Price$48
- Updated2026-06-04
- Buy
- ManufacturerAK Scientific
- Product numberI520
- Product descriptionMizolastine 98%
- Packaging1g
- Price$62
- Updated2026-06-04
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003411
- Product descriptionMIZOLASTINE 95.00%
- Packaging25MG
- Price$160.65
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003411
- Product descriptionMIZOLASTINE 95.00%
- Packaging100MG
- Price$716.1
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007C3L | 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98% | 200mg | $27 | 2026-05-28 | Buy |
| aablocks | AA007C3L | 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98% | 1g | $56 | 2026-05-28 | Buy |
| aablocks | AA007C3L | 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone ≥98% | 5g | $200 | 2026-05-28 | Buy |
| aablocks | AA007C3L | 2-[[1-[1-[(4-Fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(3H)-pyrimidinone 98% | 25g | $807 | 2026-05-28 | Buy |
| AHH | API-1754 | Mizolastine 98% | 0.1g | $370 | 2021-12-16 | Buy |
| AHH | API-1754 | Mizolastine 97% | 0.1g | $370 | 2026-05-26 | Buy |
| AK Scientific | I520 | Mizolastine 98% | 5g | $241 | 2026-06-04 | Buy |
| AK Scientific | J98981 | Mizolastine 95% | 5g | $180 | 2026-06-04 | Buy |
| AK Scientific | J10320 | Mizolastine >98%,powder | 100mg | $95 | 2026-06-04 | Buy |
| AK Scientific | J98981 | Mizolastine | 1g | $80 | 2021-12-16 | Buy |
| AK Scientific | J10320 | Mizolastine >98%,powder | 5mg | $22 | 2026-06-04 | Buy |
| AK Scientific | J98981 | Mizolastine 95% | 1g | $46 | 2026-06-04 | Buy |
| AK Scientific | J10320 | Mizolastine >98%,powder | 25mg | $48 | 2026-06-04 | Buy |
| AK Scientific | I520 | Mizolastine 98% | 1g | $62 | 2026-06-04 | Buy |
| American Custom Chemicals Corporation | API0003411 | MIZOLASTINE 95.00% | 25MG | $160.65 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0003411 | MIZOLASTINE 95.00% | 100MG | $716.1 | 2021-12-16 | Buy |
Properties
Melting point :217°
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly, Heated), DMSO, Methanol (Slightly, Heated)
form :Solid
pka :9.73±0.40(Predicted)
color :White
Merck :14,6221
InChI :1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)
InChIKey :PVLJETXTTWAYEW-UHFFFAOYSA-N
SMILES :C1(N(C2CCN(C3N(CC4=CC=C(F)C=C4)C4=CC=CC=C4N=3)CC2)C)=NC=CC(=O)N1
Density :1.34±0.1 g/cm3(Predicted)
storage temp. :Refrigerator
solubility :Chloroform (Slightly, Heated), DMSO, Methanol (Slightly, Heated)
form :Solid
pka :9.73±0.40(Predicted)
color :White
Merck :14,6221
InChI :1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)
InChIKey :PVLJETXTTWAYEW-UHFFFAOYSA-N
SMILES :C1(N(C2CCN(C3N(CC4=CC=C(F)C=C4)C4=CC=CC=C4N=3)CC2)C)=NC=CC(=O)N1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Mizolastine was marketed in Germany and Switzerland as Mizollen for the symptomatic relief of seasonal and perennial allergic rhinoconjunctivitis and urticaria. Mizolastine is a new long-acting, orally active antihistaminic agent with a rapid onset of action ; the two most recent H1 antagonists launched were fexofenadine, metabolite of terfenadine (Sepracor, 1996) and Olopatadine (Kyowa Hakko, 1997). Mizolastine can be prepared in 2 steps from 2-chloro 1- (4-fluorobenzyl)benzimidazole by successive condensations of appropriate amine and thioether. Mizolastine selectively blocks the peripheral H1 receptors (but not the serotonergic, noradrenergic, muscarinic receptors) with a minimal occupancy of brain receptors, and therefore does not elicit any sedative effects. Moreover, Mizolastine does not produce cardiac rhythm disorders which have been associated with certain non-sedating antihistamines in humans.Related product price
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Suppliers and manufacturers
Hebei Yanxi Chemical Co., Ltd.
Henan Tianfu Chemical Co.,Ltd.
Xiamen AmoyChem Co., Ltd
CONIER CHEM AND PHARMA LIMITED
HANGZHOU CLAP TECHNOLOGY CO.,LTD
AFINE CHEMICALS LIMITED
Mizolastine
CAS:108612-45-9
