NPS 2390
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- $45 - $1190
- Product name: NPS 2390
- CAS: 226878-01-9
- MF: C19H21N3O
- MW: 307.39
- EINECS:
- MDL Number:MFCD05865239
- Synonyms:N-tricyclo[3.3.1.13,7]dec-1-yl-2-quinoxalinecarboxamide;N-(1-adamantyl)quinoxaline-2-carboxamide;N-(Adamantan-1-yl)quinoxaline-2-carboxamide;Inhibitor,NPS2390,Calcium-sensing receptor,NPS-2390,mGluR,inhibit,Metabotropic glutamate receptors,CaSR,NPS 2390;2-Quinoxalinecarboxamide, N-tricyclo[3.3.1.13,7]dec-1-yl-;NPS2390, 10 mM in DMSO
11 prices
Selected condition：
Brand
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Cayman Chemical
- CSNpharm
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25MG
- 50mg
- ManufacturerAK Scientific
- Product number6596CQ
- Product descriptionN-(1-Adamantyl)quinoxaline-2-carboxamide
- Packaging5mg
- Price$197
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0003710
- Product descriptionNPS 2390 95.00%
- Packaging5MG
- Price$203.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberPEP0003710
- Product descriptionNPS 2390 95.00%
- Packaging25MG
- Price$906.53
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS2390
- Packaging10mg
- Price$282
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB5532
- Product descriptionNPS2390
- Packaging50mg
- Price$1190
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11989
- Product descriptionNPS 2390 ≥98%
- Packaging5mg
- Price$89
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11989
- Product descriptionNPS 2390 ≥98%
- Packaging10mg
- Price$168
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11989
- Product descriptionNPS 2390 ≥98%
- Packaging25mg
- Price$395
- Updated2024-03-01
- Buy
- ManufacturerCSNpharm
- Product numberCSN23007
- Product descriptionNPS2390
- Packaging50mg
- Price$604
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberN899033
- Product descriptionNPS2390
- Packaging1mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberN899033
- Product descriptionNPS2390
- Packaging5mg
- Price$75
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 6596CQ | N-(1-Adamantyl)quinoxaline-2-carboxamide | 5mg | $197 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003710 | NPS 2390 95.00% | 5MG | $203.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | PEP0003710 | NPS 2390 95.00% | 25MG | $906.53 | 2021-12-16 | Buy |
| ApexBio Technology | B5532 | NPS2390 | 10mg | $282 | 2021-12-16 | Buy |
| ApexBio Technology | B5532 | NPS2390 | 50mg | $1190 | 2021-12-16 | Buy |
| Cayman Chemical | 11989 | NPS 2390 ≥98% | 5mg | $89 | 2024-03-01 | Buy |
| Cayman Chemical | 11989 | NPS 2390 ≥98% | 10mg | $168 | 2024-03-01 | Buy |
| Cayman Chemical | 11989 | NPS 2390 ≥98% | 25mg | $395 | 2024-03-01 | Buy |
| CSNpharm | CSN23007 | NPS2390 | 50mg | $604 | 2021-12-16 | Buy |
| TRC | N899033 | NPS2390 | 1mg | $45 | 2021-12-16 | Buy |
| TRC | N899033 | NPS2390 | 5mg | $75 | 2021-12-16 | Buy |
Properties
Boiling point :542.4±30.0 °C(Predicted)
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 50 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :11.53±0.20(Predicted)
color :White to light yellow
Density :1.28±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :Soluble to 50 mM in DMSO and to 50 mM in ethanol
form :Powder
pka :11.53±0.20(Predicted)
color :White to light yellow
Safety Information
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| Signal word: | Warning | |||||||
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Description
Metabotropic glutamate receptors (mGluRs), mediate excitatory synaptic transmission in the central nervous system. Potent and selective antagonists of the type I mGluRs (mGluR1 and mGluR5) are of interest as novel therapeutics for the treatment of various CNS disorders, such as pain, epilepsy, and stroke. NPS 2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 with IC50 values equal to 5.2 and 82 nM, respectively). At concentrations up to 30 μM, NPS 2390 does not affect mGluR2 or mGluR8 or a standard collection of 37 additional receptors, ion channels, and enzymes. At a dose of 10 mg/kg, NPS 2390 displaced the specifically bound mGlu1R-selective antagonist, [3H]R214127, in rat cerebellum.Suppliers and manufacturers
ATK CHEMICAL COMPANY LIMITED
Nantong HI-FUTURE Biology Co., Ltd.
TargetMol Chemicals Inc.
Wuhan Topule Biopharmaceutical Co., Ltd
Aladdin Scientific
Compound Net Biotechnology Inc.
DKMbiochem.Co. Ltd
HangZhou YuHao Chemical Technology Co., Ltd.
Shanghai Lollane Biological Technology Co.,Ltd.
