Obeticholic Acid
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- $20 - $800
- Product name: Obeticholic Acid
- CAS: 459789-99-2
- MF: C26H44O4
- MW: 420.63
- EINECS:810-245-2
- MDL Number:MFCD16621104
- Synonyms:6-Ethylchenodeoxycholic aicd;3A, 7A -DIHYDROXY-6A -ETHYL-5B-CHOLAN-24-OIC ACID;Obeticholic acid 6-ECDCA;6alpha-Ethyl-chenodeoxycholic acid;6-Ecdca;6-Ethylchenodeoxycholic acid;6alph;Obeticholic Acid(INT 747,6-ECDCA)
49 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Axon Medchem
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Sigma-Aldrich
- TRC
Package
- 250mg
- 500mg
- 1g
- 1.00g
- 5.00g
- 5g
- 10.00g
- 1mlx10mM(inDMSO)
- 25mg
- 100mg
- 200mg
- 10mM(in1mLDMSO)
- 5mg
- 10mg
- 50mg
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M005
- Product description6-ECDCA ≥95%(NMR)
- Packaging5mg
- Price$20
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M025
- Product description6-ECDCA ≥95%(NMR)
- Packaging25mg
- Price$80
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M025
- Product description6-ECDCA ≥95%(NMR)
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CR1-3560-M100
- Product description6-ECDCA ≥95%(NMR)
- Packaging100mg
- Price$200
- Updated2026-05-06
- Buy
- ManufacturerAK Scientific
- Product numberY1328
- Product descriptionINT-747
- Packaging100mg
- Price$290
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholic Acid
- Packaging100mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholic Acid
- Packaging25mg
- Price$165
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging25mg
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging5mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholic Acid
- Packaging5mg
- Price$55
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholic Acid
- Packaging10mM(in1mLDMSO)
- Price$61
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberB4888
- Product descriptionObeticholicAcid
- Packaging100mg
- Price$470
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3174
- Product descriptionObeticholic acid 98%
- Packaging10mg
- Price$77
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon3174
- Product descriptionObeticholic acid 98%
- Packaging50mg
- Price$231
- Updated2026-05-19
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1307446
- Product descriptionObeticholic Acid 99.97%(Mayvarybetweenbatches)
- Packaging100mg
- Price$210
- Updated2026-05-06
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb1307446
- Product descriptionObeticholic Acid 99.97%(Mayvarybetweenbatches)
- Packaging25mg
- Price$120
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | AG-CR1-3560-M005 | 6-ECDCA ≥95%(NMR) | 5mg | $20 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M025 | 6-ECDCA ≥95%(NMR) | 25mg | $80 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M025 | 6-ECDCA ≥95%(NMR) | 25mg | $200 | 2021-12-16 | Buy |
| Adipogen Life Sciences | AG-CR1-3560-M100 | 6-ECDCA ≥95%(NMR) | 100mg | $200 | 2026-05-06 | Buy |
| AK Scientific | Y1328 | INT-747 | 100mg | $290 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | Obeticholic Acid | 100mg | $220 | 2026-05-06 | Buy |
| ApexBio Technology | B4888 | Obeticholic Acid | 25mg | $165 | 2026-05-06 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 25mg | $200 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 5mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | B4888 | Obeticholic Acid | 5mg | $55 | 2026-05-06 | Buy |
| ApexBio Technology | B4888 | Obeticholic Acid | 10mM(in1mLDMSO) | $61 | 2026-05-06 | Buy |
| ApexBio Technology | B4888 | ObeticholicAcid | 100mg | $470 | 2021-12-16 | Buy |
| Axon Medchem | Axon3174 | Obeticholic acid 98% | 10mg | $77 | 2026-05-19 | Buy |
| Axon Medchem | Axon3174 | Obeticholic acid 98% | 50mg | $231 | 2026-05-19 | Buy |
| Biorbyt Ltd | orb1307446 | Obeticholic Acid 99.97%(Mayvarybetweenbatches) | 100mg | $210 | 2026-05-06 | Buy |
| Biorbyt Ltd | orb1307446 | Obeticholic Acid 99.97%(Mayvarybetweenbatches) | 25mg | $120 | 2026-05-06 | Buy |
Properties
Melting point :108-110 °C
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Boiling point :562.9±25.0 °C(Predicted)
Density :1.091
storage temp. :-20°C
solubility :Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 25 mg/ml)
form :White solid.
pka :4.76±0.10(Predicted)
color :White
optical activity :[α]/D +4 to +6°, c =1.0 in methanol
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 2 months.
InChIKey :ZXERDUOLZKYMJM-IMGBAYNYNA-N
SMILES :C[C@]12CC[C@@H](O)C[C@@]1([H])[C@@H](CC)[C@@H](O)[C@@]1([H])[C@]3([H])CC[C@]([H])([C@H](C)CCC(=O)O)[C@@]3(C)CC[C@]21[H] |&1:1,4,7,9,12,14,16,20,22,29,33,r|
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Obeticholic acid is a potent and selective farnesoid X receptor agonist that promotes the flow of bile in the liver. The drug was approved by the USFDA for the treatment of the rare chronic liver disease primary biliary cholangitis (PBC) in combination with ursodeoxycholic acid (UDCA) in adults with inadequate response to UDCA or as a single agent therapy in adults unable to tolerate UDCA. Obeticholic acid was discovered at the Università de Perugia and developed by Intercept Pharmaceuticals. Obeticholic acid has also been granted orphan drug designation for the treatment of primary sclerosing cholangitis and primary biliary cirrhosis and has received breakthrough therapy designation for the treatment of patients with nonalcohol steatohepatitis (NASH) with liver fibrosis.Suppliers and manufacturers
Capot Chemical Co.,Ltd.
Nanjing Gold Pharmaceutical Technology Co. Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
