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ChemicalBook >> CAS DataBase List >> RbBP5 (human recombinant)

RbBP5 (human recombinant)

RbBP5 (human recombinant) price.
1 prices
Selected condition:
Brand
  • Cayman Chemical
Package
  • 50μg
  • ManufacturerCayman Chemical
  • Product number10947
  • Product descriptionRbBP5 (human, recombinant) ≥80%
  • Packaging50μg
  • Price$456
  • Updated2026-04-30
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 10947 RbBP5 (human, recombinant) ≥80% 50μg $456 2026-04-30 Buy

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Description

Retinoblastoma-binding protein 5 (RbBP5) is a ubiquitously expressed nuclear protein that contains WD40 repeat-like domains. RbBP5 binds directly to tumor suppressor retinoblastoma protein (RB) and regulates cell proliferation. Interaction of RbBP5 occurs preferentially with underphosphorylated RB through the E1A-binding pocket B. RbBP5 is also an important component of the multi-subunit SET1 lysine methyltransferase protein complex, which includes MLL1. RbBP5 interacts directly with WDR5 contributing to the activation of the MLL1 core protein complex. MLL1-4 protein complexes catalyze the di- and trimethylation of histone H3 at lysine 4 (H3K4me2/me3), leading to the maintenance of global H3K4 trimethylation.

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