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ChemicalBook >> CAS DataBase List >> STAT5 Inhibitor

STAT5 Inhibitor

STAT5 Inhibitor price.
  • $59 - $1350
  • Product name: STAT5 Inhibitor
  • CAS: 285986-31-4
  • MF: C16H11N3O3
  • MW: 293.28
  • EINECS:604-604-1
  • MDL Number:MFCD00124694
  • Synonyms:STAT5 Inhibitor;CS-2509;STAT5-IN-1;N'-[(4-oxo-4H-chromen-3-yl)methylene]nicotinohydrazide;STAT5 Inhibitor 1;(E)-N'-((4-oxo-4H-chromen-3-yl)methylene)nicotinohydrazide;MDK6314;3-Pyridinecarboxylic acid, 2-[(4-oxo-4H-1-benzopyran-3-yl)methylene]hydrazide
21 prices
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Brand
  • Ambeed
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Sigma-Aldrich
Package
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 1g
  • ManufacturerAmbeed
  • Product numberA303941
  • Product descriptionSTAT5Inhibitor 98+%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA303941
  • Product descriptionSTAT5Inhibitor 98+%
  • Packaging10mg
  • Price$107
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA303941
  • Product descriptionSTAT5Inhibitor 98+%
  • Packaging25mg
  • Price$188
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4105
  • Product descriptionSTAT5Inhibitor
  • Packaging5mg
  • Price$77
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC4105
  • Product descriptionSTAT5Inhibitor
  • Packaging25mg
  • Price$324
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2731
  • Product descriptionSTAT5Inhibitor1[285986-31-4] 98%
  • Packaging10mg
  • Price$99
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon2731
  • Product descriptionSTAT5Inhibitor1[285986-31-4] 98%
  • Packaging50mg
  • Price$330
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number15784
  • Product descriptionSTAT5 Inhibitor ≥95%
  • Packaging5mg
  • Price$68
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15784
  • Product descriptionSTAT5 Inhibitor ≥95%
  • Packaging10mg
  • Price$130
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number15784
  • Product descriptionSTAT5 Inhibitor ≥95%
  • Packaging25mg
  • Price$286
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM251923
  • Product descriptionSTAT5Inhibitor 98%
  • Packaging100mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6859
  • Product descriptionSTAT5-IN-1 >98.0%
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6859
  • Product descriptionSTAT5-IN-1 >98.0%
  • Packaging10mg
  • Price$108
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-6859
  • Product descriptionSTAT5-IN-1 >98.0%
  • Packaging25mg
  • Price$228
  • Updated2021-12-16
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  • ManufacturerChemScene
  • Product numberCS-6859
  • Product descriptionSTAT5-IN-1 >98.0%
  • Packaging100mg
  • Price$720
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD00005000
  • Product descriptionSTAT5Inhibitor 98+%
  • Packaging10mg
  • Price$59
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Ambeed A303941 STAT5Inhibitor 98+% 5mg $60 2021-12-16 Buy
Ambeed A303941 STAT5Inhibitor 98+% 10mg $107 2021-12-16 Buy
Ambeed A303941 STAT5Inhibitor 98+% 25mg $188 2021-12-16 Buy
ApexBio Technology C4105 STAT5Inhibitor 5mg $77 2021-12-16 Buy
ApexBio Technology C4105 STAT5Inhibitor 25mg $324 2021-12-16 Buy
Axon Medchem Axon2731 STAT5Inhibitor1[285986-31-4] 98% 10mg $99 2021-12-16 Buy
Axon Medchem Axon2731 STAT5Inhibitor1[285986-31-4] 98% 50mg $330 2021-12-16 Buy
Cayman Chemical 15784 STAT5 Inhibitor ≥95% 5mg $68 2024-03-01 Buy
Cayman Chemical 15784 STAT5 Inhibitor ≥95% 10mg $130 2024-03-01 Buy
Cayman Chemical 15784 STAT5 Inhibitor ≥95% 25mg $286 2024-03-01 Buy
Chemenu CM251923 STAT5Inhibitor 98% 100mg $159 2021-12-16 Buy
ChemScene CS-6859 STAT5-IN-1 >98.0% 5mg $60 2021-12-16 Buy
ChemScene CS-6859 STAT5-IN-1 >98.0% 10mg $108 2021-12-16 Buy
ChemScene CS-6859 STAT5-IN-1 >98.0% 25mg $228 2021-12-16 Buy
ChemScene CS-6859 STAT5-IN-1 >98.0% 100mg $720 2021-12-16 Buy
Crysdot CD00005000 STAT5Inhibitor 98+% 10mg $59 2021-12-16 Buy

Properties

Melting point :214-216 °C
Density :1.33±0.1 g/cm3(Predicted)
storage temp. :2-8°C(protect from light)
solubility :≥9.58 mg/mL in DMSO; insoluble in EtOH; insoluble in H2O
form :crystalline solid
pka :10.44±0.46(Predicted)
color :White to light yellow

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
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Description

Signal Transducers and Activators of Transcriptions (STATs) are a family of cytoplasmic latent transcription factors that are activated to regulate gene expression in response to a large number of extracellular signaling polypeptides including cytokines, interferons, and growth factors. STAT5, which consists of two isoforms STAT5α and STAT5β, is known to be overactive in several kinds of leukemias and various solid tumors. STAT5 Inhibitor is a cell-permeable, nonpetidic nicotinoyl hydrazone that suppresses STAT5 by targeting its SH2 domain (IC50 = 47 μM against STAT5β SH2 domain EPO peptide binding activity). Comparatively, this compound exhibits reduced potency towards inhibiting the SH2 domain of STAT1, STAT3, or Lck (IC50 > 500 μM). STAT5 Inhibitor has been shown to block STAT5/STAT5 DNA binding in K562 nuclear extracts.