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ChemicalBook >> CAS DataBase List >> SU 6668

SU 6668

$5 - $1350
Product name: SU 6668
CAS: 210644-62-5
MF: C18H18N2O3
MW: 310.35
EINECS:
MDL Number:MFCD09743433
Synonyms:SU 6668;3-(2,4-Dimethyl-5-(2-oxo-1,2-dihydroindol-3-ylidenemethyl)-1H-pyrrol-3-yl)-propionic acid;1H-Pyrrole-3-propanoic acid, 5-((Z)-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-;5-((Z)-1,2-Dihydro-2-oxo-3H-indol-3-ylidene)methyl)-2,4-dimethyl-1H-pyrrole-3-propanoic acid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668;3-[2,4-dimethyl-5-[(Z)-(2-oxo-1H-indol-3-ylidene)methyl]-1H-pyrrol-3-yl]propanoicacid;PDGFR Tyrosine Kinase Inhibitor VI, SU6668 - CAS 210644-62-5 - Calbiochem;3-(2,4-Dimethyl-5-{[(3Z)-2-oxo-1H-indol-3-ylidene]methyl}-1H-pyrrol-3-yl)propanoic acid

Price29 Properties Safety Information Description

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Ambeed
AvaChem
Axon Medchem
Chemenu
ChemScene
Crysdot
CSNpharm
Matrix Scientific
Sigma-Aldrich
Tocris
TRC
Usbiological

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5mg
10mg
25mg
50mg
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250mg
250.00mg
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ManufacturerAmbeed
Product numberA146183
Product descriptionSU6668 97%
Packaging25mg
Price$5
Updated2021-12-16
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ManufacturerAmbeed
Product numberA146183
Product descriptionSU6668 97%
Packaging5g
Price$405
Updated2021-12-16
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ManufacturerAvaChem
Product number4723
Product descriptionOrantinib; SU-6668 97%
Packaging1g
Price$690
Updated2026-05-22
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ManufacturerAvaChem
Product number4723
Product descriptionOrantinib; SU-6668 97%
Packaging5mg
Price$59
Updated2026-05-22
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ManufacturerAvaChem
Product number4723
Product descriptionOrantinib; SU-6668 97%
Packaging10mg
Price$79
Updated2026-05-22
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ManufacturerAvaChem
Product number4723
Product descriptionOrantinib; SU-6668 97%
Packaging25mg
Price$129
Updated2026-05-22
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ManufacturerAvaChem
Product number4723
Product descriptionOrantinib; SU-6668 97%
Packaging100mg
Price$239
Updated2026-05-22
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ManufacturerAxon Medchem
Product numberAxon1891
Product descriptionSU 6668
Packaging50mg
Price$363
Updated2026-05-19
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ManufacturerAxon Medchem
Product numberAxon1891
Product descriptionSU 6668
Packaging10mg
Price$110
Updated2026-05-19
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ManufacturerChemenu
Product numberCM147636
Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+
Packaging5g
Price$292
Updated2026-05-20
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ManufacturerChemenu
Product numberCM147636
Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+
Packaging5g
Price$292
Updated2026-05-26
Buy

ManufacturerChemenu
Product numberCM147636
Product description(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+
Packaging1g
Price$491
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-0102969
Product description(Z)-Orantinib 99.02%
Packaging50mg
Price$432
Updated2021-12-16
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ManufacturerChemScene
Product numberCS-0102969
Product description(Z)-Orantinib 99.02%
Packaging100mg
Price$756
Updated2021-12-16
Buy

ManufacturerChemScene
Product numberCS-0102969
Product description(Z)-Orantinib 99.02%
Packaging10mg
Price$108
Updated2021-12-16
Buy

ManufacturerCrysdot
Product numberCD11166850
Product descriptionSU6668 97%
Packaging250mg
Price$218
Updated2021-12-16
Buy

Manufacturer	Product number	Product description	Packaging	Price	Updated	Buy
Ambeed	A146183	SU6668 97%	25mg	$5	2021-12-16	Buy
Ambeed	A146183	SU6668 97%	5g	$405	2021-12-16	Buy
AvaChem	4723	Orantinib; SU-6668 97%	1g	$690	2026-05-22	Buy
AvaChem	4723	Orantinib; SU-6668 97%	5mg	$59	2026-05-22	Buy
AvaChem	4723	Orantinib; SU-6668 97%	10mg	$79	2026-05-22	Buy
AvaChem	4723	Orantinib; SU-6668 97%	25mg	$129	2026-05-22	Buy
AvaChem	4723	Orantinib; SU-6668 97%	100mg	$239	2026-05-22	Buy
Axon Medchem	Axon1891	SU 6668	50mg	$363	2026-05-19	Buy
Axon Medchem	Axon1891	SU 6668	10mg	$110	2026-05-19	Buy
Chemenu	CM147636	(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+	5g	$292	2026-05-20	Buy
Chemenu	CM147636	(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoic acid 95%+	5g	$292	2026-05-26	Buy
Chemenu	CM147636	(Z)-3-(2,4-Dimethyl-5-((2-oxoindolin-3-ylidene)-methyl)-1H-pyrrol-3-yl)propanoicacid 95%+	1g	$491	2021-12-16	Buy
ChemScene	CS-0102969	(Z)-Orantinib 99.02%	50mg	$432	2021-12-16	Buy
ChemScene	CS-0102969	(Z)-Orantinib 99.02%	100mg	$756	2021-12-16	Buy
ChemScene	CS-0102969	(Z)-Orantinib 99.02%	10mg	$108	2021-12-16	Buy
Crysdot	CD11166850	SU6668 97%	250mg	$218	2021-12-16	Buy

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Properties

storage temp. :+2C to +8C
solubility :DMSO : 50 mg/mL (161.11 mM; Need ultrasonic)
form :Dark yellow solid
color :Orange to red
InChI :1S/C18H18N2O3/c1-10-12(7-8-17(21)22)11(2)19-16(10)9-14-13-5-3-4-6-15(13)20-18(14)23/h3-6,9,19H,7-8H2,1-2H3,(H,20,23)(H,21,22)/b14-9-
InChIKey :NHFDRBXTEDBWCZ-ZROIWOOFSA-N
SMILES :CC1=C(C(C)=C(/C=C2C(NC3=CC=CC=C\23)=O)N1)CCC(O)=O

Safety Information

Symbol(GHS):

Signal word:

Hazard statements:

Code	Hazard statements	Hazard class	Category	Signal word	Pictogram	P-Codes

Precautionary statements:

Description

PDGFR Tyrosine Kinase Inhibitor VI, SU6668 is a cell-permeable indolinone compound that acts as a potent ATP-competitive inhibitor against RTKs (receptor tyrosine kinases) Kit, PDGFRβ, VEGFR2 (Flk-1/KDR), FGFR1 activity in vitro (IC₅₀ = 0.01, 0.1, 3.9, and 3.8 M, respectively) and PDGF/VEGF/bFGF-mediated angiogenesis and tumor development. Although initially characterized as an RTK inhibitor, SU6668 is now also known to target ser/thr kinases Aurora A, Aurora B, TBK1 (NAK/T2K), and AMPK (IC₅₀ = 0.85, 0.047, 1.4, and 1.8 M, respectively), as well as non-receptor TKs Lyn and Yes (IC₅₀ = 4.3 and 5.8 M, respectively).

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Suppliers and manufacturers

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SU 6668

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