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ChemicalBook >> CAS DataBase List >> Tetramethyl orthosilicate

Tetramethyl orthosilicate

Tetramethyl orthosilicate price.
  • $33.6 - $710
  • Product name: Tetramethyl orthosilicate
  • CAS: 681-84-5
  • MF: C4H12O4Si
  • MW: 152.22
  • EINECS:211-656-4
  • MDL Number:MFCD00008341
  • Synonyms:Dynasil M;Methyl orthosilicate;Methyl silicate ((CH3)4SiO4);Methyl silicate ((MeO)4Si);methylesterofortho-silicicaci ;methylorthosilicate ;methylsilicate((ch3)4sio4) ;methylsilicate[(meo)4si]
20 prices
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  • Sigma-Aldrich
  • Strem Chemicals
  • Thermo Scientific Chemicals
  • TRC
Package
  • 25g
  • 25mL
  • 50g
  • 100g
  • 100ML
  • 250ml
  • 500g
  • 1l
  • 25 g
  • 100 g
  • 500 g
  • ManufacturerSigma-Aldrich
  • Product number8.14651
  • Product descriptionTetramethyl orthosilicate for synthesis
  • Packaging25mL
  • Price$58.8
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number8.14651
  • Product descriptionTetramethyl orthosilicate for synthesis
  • Packaging100ML
  • Price$64.8
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number341436
  • Product descriptionTetramethyl orthosilicate ≥99%
  • Packaging25g
  • Price$68.6
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product number218472
  • Product descriptionTetramethyl orthosilicate 98%
  • Packaging100g
  • Price$116
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product number679259
  • Product descriptionTetramethyl orthosilicate deposition grade, ≥98%, ≥99.9% trace metals basis
  • Packaging50g
  • Price$120
  • Updated2023-06-20
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number341436
  • Product descriptionTetramethyl orthosilicate ≥99%
  • Packaging100g
  • Price$155
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number218472
  • Product descriptionTetramethyl orthosilicate 98%
  • Packaging500g
  • Price$200
  • Updated2026-04-30
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number87682
  • Product descriptionTetramethyl orthosilicate purum, ≥98.0% (GC)
  • Packaging250ml
  • Price$257
  • Updated2026-04-30
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  • ManufacturerSigma-Aldrich
  • Product number87682
  • Product descriptionTetramethyl orthosilicate purum, ≥98.0% (GC)
  • Packaging1l
  • Price$710
  • Updated2026-04-30
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  • ManufacturerStrem Chemicals
  • Product number93-1459
  • Product descriptionTetramethoxysilane, 98%
  • Packaging100g
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerStrem Chemicals
  • Product number93-1459
  • Product descriptionTetramethoxysilane, 98% 98%
  • Packaging100g
  • Price$114
  • Updated2026-04-30
  • Buy
  • ManufacturerStrem Chemicals
  • Product number93-1459
  • Product descriptionTetramethoxysilane, 98%
  • Packaging25g
  • Price$37
  • Updated2024-03-01
  • Buy
  • ManufacturerStrem Chemicals
  • Product number93-1459
  • Product descriptionTetramethoxysilane, 98% 98%
  • Packaging25g
  • Price$40
  • Updated2026-04-30
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  • ManufacturerThermo Scientific Chemicals
  • Product number20382
  • Product descriptionTetramethyl orthosilicate, 99% 99%
  • Packaging25 g
  • Price$44.65
  • Updated2026-04-24
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  • ManufacturerThermo Scientific Chemicals
  • Product numberL09716
  • Product descriptionTetramethoxysilane 98%
  • Packaging100g
  • Price$88.4
  • Updated2026-04-24
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  • ManufacturerThermo Scientific Chemicals
  • Product number20382
  • Product descriptionTetramethyl orthosilicate, 99% 99%
  • Packaging100 g
  • Price$91.65
  • Updated2026-04-24
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Sigma-Aldrich 8.14651 Tetramethyl orthosilicate for synthesis 25mL $58.8 2026-04-30 Buy
Sigma-Aldrich 8.14651 Tetramethyl orthosilicate for synthesis 100ML $64.8 2026-04-30 Buy
Sigma-Aldrich 341436 Tetramethyl orthosilicate ≥99% 25g $68.6 2026-04-30 Buy
Sigma-Aldrich 218472 Tetramethyl orthosilicate 98% 100g $116 2026-04-30 Buy
Sigma-Aldrich 679259 Tetramethyl orthosilicate deposition grade, ≥98%, ≥99.9% trace metals basis 50g $120 2023-06-20 Buy
Sigma-Aldrich 341436 Tetramethyl orthosilicate ≥99% 100g $155 2026-04-30 Buy
Sigma-Aldrich 218472 Tetramethyl orthosilicate 98% 500g $200 2026-04-30 Buy
Sigma-Aldrich 87682 Tetramethyl orthosilicate purum, ≥98.0% (GC) 250ml $257 2026-04-30 Buy
Sigma-Aldrich 87682 Tetramethyl orthosilicate purum, ≥98.0% (GC) 1l $710 2026-04-30 Buy
Strem Chemicals 93-1459 Tetramethoxysilane, 98% 100g $108 2024-03-01 Buy
Strem Chemicals 93-1459 Tetramethoxysilane, 98% 98% 100g $114 2026-04-30 Buy
Strem Chemicals 93-1459 Tetramethoxysilane, 98% 25g $37 2024-03-01 Buy
Strem Chemicals 93-1459 Tetramethoxysilane, 98% 98% 25g $40 2026-04-30 Buy
Thermo Scientific Chemicals 20382 Tetramethyl orthosilicate, 99% 99% 25 g $44.65 2026-04-24 Buy
Thermo Scientific Chemicals L09716 Tetramethoxysilane 98% 100g $88.4 2026-04-24 Buy
Thermo Scientific Chemicals 20382 Tetramethyl orthosilicate, 99% 99% 100 g $91.65 2026-04-24 Buy

Properties

Melting point :−4 °C(lit.)
Boiling point :121-122 °C(lit.)
Density :1.023 g/mL at 25 °C(lit.)
vapor density :5.25 (vs air)
vapor pressure :3.35 psi ( 20 °C)
FEMA :3185 | METHYLATED SILICA
refractive index :n20/D 1.368(lit.)
Flash point :84 °F
storage temp. :Store below +30°C.
form :liquid
color :colorless
Specific Gravity :1.032
explosive limit :0.88-23.8%(V)
Water Solubility :hydrolysis
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
Sensitive :Moisture Sensitive
BRN :1699658
Henry's Law Constant :1.5×100 mol/(m3Pa) at 25℃, HSDB (2015)
InChI :1S/C4H12O4Si/c1-5-9(6-2,7-3)8-4/h1-4H3
InChIKey :LFQCEHFDDXELDD-UHFFFAOYSA-N
SMILES :[Si](OC)(OC)(OC)OC
CAS DataBase Reference :681-84-5(CAS DataBase Reference)
NIST Chemistry Reference :Tetramethyl silicate(681-84-5)
EPA Substance Registry System :Tetramethyl silicate (681-84-5)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H330 Fatal if inhaled Acute toxicity,inhalation Category 1, 2 Danger GHS hazard pictograms P260, P271, P284, P304+P340, P310,P320, P403+P233, P405, P501
H371 May cause damage to organs Specific target organ toxicity, single exposure Category 2 Warning P260, P264, P270, P309+P311, P405,P501
H372 Causes damage to organs through prolonged or repeated exposure Specific target organ toxicity, repeated exposure Category 1 Danger GHS hazard pictograms P260, P264, P270, P314, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P284 Wear respiratory protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P370+P378 In case of fire: Use … for extinction.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.
P403+P235 Store in a well-ventilated place. Keep cool.
P405 Store locked up.
P501 Dispose of contents/container to..…

Description

Tetramethyl orthosilicate (TMOS) is popularly used in the sol-gel synthesis of silicates1 and chromium-doped silicates and in the formation of hexagonal mesoporous silica layers.

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