VARESPLADIB
|
- $42 - $5133
- Product name: VARESPLADIB
- CAS: 172732-68-2
- MF: C21H20N2O5
- MW: 380.39
- EINECS:1592732-453-0
- MDL Number:MFCD00944812
- Synonyms:VARESPLADIB;LY315920(Varespladib);[[3-(Aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid;LY-333013;Varespladib (LY315920);2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid;2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid;CS-2393
62 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TRC
- Usbiological
Package
- 10mM*1mLinDMSO(Solution)
- 1mg
- 10mM*1mLinDMSO
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- 250MG
- 1000mg
- 10mM*1mLinDMSO(Solid+Solvent)
- 1G
- 10g
- 10mM(in1mLDMSO)
- 10mM(in 1mL DMSO)
- Manufactureraablocks
- Product numberAA007VMG
- Product descriptionVarespladib 98%(HPLC)
- Packaging1mg
- Price$42
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VMG
- Product descriptionVarespladib 98%(HPLC)
- Packaging5mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VMG
- Product descriptionVarespladib 98%
- Packaging10mg
- Price$97
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VMG
- Product descriptionVarespladib 98%
- Packaging25mg
- Price$168
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA007VMG
- Product descriptionVarespladib 98%
- Packaging50mg
- Price$250
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33750
- Product descriptionVarespladib 98%
- Packaging100MG
- Price$645
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33750
- Product descriptionVarespladib 98%
- Packaging250MG
- Price$1220
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberO33750
- Product descriptionVarespladib 98%
- Packaging1G
- Price$3660
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product numberY0326
- Product descriptionVarespladib
- Packaging100mg
- Price$660
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberSYN5645
- Product descriptionVarespladib
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0028124
- Product descriptionVARESPLADIB 95.00%
- Packaging5MG
- Price$458.94
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4356
- Product descriptionVarespladib (LY315920)
- Packaging50mg
- Price$330
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4356
- Product descriptionVarespladib (LY315920)
- Packaging25mg
- Price$220
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4356
- Product descriptionVarespladib (LY315920)
- Packaging10mg
- Price$110
- Updated2026-05-06
- Buy
- ManufacturerApexBio Technology
- Product numberA4356
- Product descriptionVarespladib(LY315920)
- Packaging10mM(in 1mL DMSO)
- Price$66
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA4356
- Product descriptionVarespladib (LY315920)
- Packaging10mM(in1mLDMSO)
- Price$66
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA007VMG | Varespladib 98%(HPLC) | 1mg | $42 | 2026-05-28 | Buy |
| aablocks | AA007VMG | Varespladib 98%(HPLC) | 5mg | $82 | 2026-05-28 | Buy |
| aablocks | AA007VMG | Varespladib 98% | 10mg | $97 | 2026-05-28 | Buy |
| aablocks | AA007VMG | Varespladib 98% | 25mg | $168 | 2026-05-28 | Buy |
| aablocks | AA007VMG | Varespladib 98% | 50mg | $250 | 2026-05-28 | Buy |
| ACHEMBLOCK | O33750 | Varespladib 98% | 100MG | $645 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33750 | Varespladib 98% | 250MG | $1220 | 2026-05-27 | Buy |
| ACHEMBLOCK | O33750 | Varespladib 98% | 1G | $3660 | 2026-05-27 | Buy |
| AK Scientific | Y0326 | Varespladib | 100mg | $660 | 2021-12-16 | Buy |
| AK Scientific | SYN5645 | Varespladib | 50mg | $547 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0028124 | VARESPLADIB 95.00% | 5MG | $458.94 | 2021-12-16 | Buy |
| ApexBio Technology | A4356 | Varespladib (LY315920) | 50mg | $330 | 2026-05-06 | Buy |
| ApexBio Technology | A4356 | Varespladib (LY315920) | 25mg | $220 | 2026-05-06 | Buy |
| ApexBio Technology | A4356 | Varespladib (LY315920) | 10mg | $110 | 2026-05-06 | Buy |
| ApexBio Technology | A4356 | Varespladib(LY315920) | 10mM(in 1mL DMSO) | $66 | 2021-12-16 | Buy |
| ApexBio Technology | A4356 | Varespladib (LY315920) | 10mM(in1mLDMSO) | $66 | 2026-05-06 | Buy |
Properties
Melting point :230-234 °C
Boiling point :667.9±65.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :3.12±0.40(Predicted)
color :white to beige
InChI :1S/C21H20N2O5.Na/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13;/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25);/q;+1/p-1
InChIKey :XZZUHXILQXLTGV-UHFFFAOYSA-M
SMILES :[Na+].[n]2(c3c(c(ccc3)OCC(=O)[O-])c(c2CC)C(=O)C(=O)N)Cc1ccccc1
Boiling point :667.9±65.0 °C(Predicted)
Density :1.32±0.1 g/cm3(Predicted)
storage temp. :-20°C
solubility :DMSO (Slightly), Methanol (Slightly)
form :powder
pka :3.12±0.40(Predicted)
color :white to beige
InChI :1S/C21H20N2O5.Na/c1-2-14-19(20(26)21(22)27)18-15(9-6-10-16(18)28-12-17(24)25)23(14)11-13-7-4-3-5-8-13;/h3-10H,2,11-12H2,1H3,(H2,22,27)(H,24,25);/q;+1/p-1
InChIKey :XZZUHXILQXLTGV-UHFFFAOYSA-M
SMILES :[Na+].[n]2(c3c(c(ccc3)OCC(=O)[O-])c(c2CC)C(=O)C(=O)N)Cc1ccccc1
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||||||
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Description
LY315920 is an inhibitor of human group IIA (hGIIA) secretory phospholipase A2 (sPLA2; IC50 = 9 nM). It also potently inhibits human GIIE and GX isoforms, as well as the corresponding mouse isoforms, but poorly inhibits other PLA2 enzymes. LY315920 inhibits sPLA2-induced release of thromboxane A2 from isolated guinea pig lung bronchoalveolar lavage cells (IC50 = 0.79 μM). Intravenous or oral administration of LY315920 to transgenic mice expressing human sPLA2 inhibits serum sPLA2 activity in a dose-related manner over four hours.Related product price
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