WITHAFERIN A
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- $25 - $7875
- Product name: WITHAFERIN A
- CAS: 5119-48-2
- MF: C28H38O6
- MW: 470.6
- EINECS:999-999-2
- MDL Number:MFCD10687098
- Synonyms:WITHAFERIN A;5,6-beta-epoxy-4-beta,22,27-trihydroxy-1-5-beta-ergosta-24-dien-26-oicacid ;delta-lactone,(20s,22r)-oxo ;nsc-101088 ;(4β,5β,6β,22R)-5,6-Epoxy-4,22,27-trihydroxy-1-oxoergosta-2,24-dien-26-oicacidδ-lactone;NSC 273757;Withaferine;(20S,22R)-5,6β-Epoxy-4β,22,27-trihydroxy-1-oxo-5β-ergosta- 2,24-dien-26-oic Acid δ-Lactone
85 prices
Selected condition:
Brand
- A1 Biochem Labs
- aablocks
- ACHEMBLOCK
- Adipogen Life Sciences
- American Custom Chemicals Corporation
- ApexBio Technology
- Apolloscientific
- Arctom
- AvaChem
- Biorbyt Ltd
- Biosynth
- Cayman Chemical
- Chemenu
- Chem-Impex
- ChemScene
- Frontier Specialty Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 1
- 1mg
- 2mg
- 5mg
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 250mg
- 500mg
- 10mM*1mLinDMSO(Solution)
- 1g
- 5g
- 10mM*1mLinDMSO(Solid+Solvent)
- ManufacturerA1 Biochem Labs
- Product numberA1-06845
- Product descriptionWithaferin A 0.95
- Packaging1g
- Price$1800
- Updated2026-06-05
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging1mg
- Price$25
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging5mg
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging10mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging25mg
- Price$169
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging100mg
- Price$513
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00DCUK
- Product descriptionWithaferin A 98%
- Packaging250mg
- Price$1070
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106698
- Product descriptionWithaferin A 98.00%
- Packaging250MG
- Price$210
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberU106698
- Product descriptionWithaferin A 98.00%
- Packaging25MG
- Price$85
- Updated2026-05-27
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0490-M001
- Product descriptionWithaferin A ≥98%(HPLC)
- Packaging1mg
- Price$70
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0490-M005
- Product descriptionWithaferin A ≥98%(HPLC)
- Packaging5mg
- Price$210
- Updated2026-05-06
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberAG-CN2-0490-M010
- Product descriptionWithaferin A ≥98%(HPLC)
- Packaging10mg
- Price$340
- Updated2026-05-06
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007135
- Product descriptionWITHAFERIN A 95.00%
- Packaging5MG
- Price$902.3
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007135
- Product descriptionWITHAFERIN A 95.00%
- Packaging1MG
- Price$650.27
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberSHG0007135
- Product descriptionWITHAFERIN A 95.00%
- Packaging10MG
- Price$583.8
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7199
- Product descriptionWithaferin A
- Packaging5mg
- Price$360
- Updated2026-05-06
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| A1 Biochem Labs | A1-06845 | Withaferin A 0.95 | 1g | $1800 | 2026-06-05 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 1mg | $25 | 2026-05-28 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 5mg | $50 | 2026-05-28 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 10mg | $82 | 2026-05-28 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 25mg | $169 | 2026-05-28 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 100mg | $513 | 2026-05-28 | Buy |
| aablocks | AA00DCUK | Withaferin A 98% | 250mg | $1070 | 2026-05-28 | Buy |
| ACHEMBLOCK | U106698 | Withaferin A 98.00% | 250MG | $210 | 2026-05-27 | Buy |
| ACHEMBLOCK | U106698 | Withaferin A 98.00% | 25MG | $85 | 2026-05-27 | Buy |
| Adipogen Life Sciences | AG-CN2-0490-M001 | Withaferin A ≥98%(HPLC) | 1mg | $70 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0490-M005 | Withaferin A ≥98%(HPLC) | 5mg | $210 | 2026-05-06 | Buy |
| Adipogen Life Sciences | AG-CN2-0490-M010 | Withaferin A ≥98%(HPLC) | 10mg | $340 | 2026-05-06 | Buy |
| American Custom Chemicals Corporation | SHG0007135 | WITHAFERIN A 95.00% | 5MG | $902.3 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007135 | WITHAFERIN A 95.00% | 1MG | $650.27 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | SHG0007135 | WITHAFERIN A 95.00% | 10MG | $583.8 | 2021-12-16 | Buy |
| ApexBio Technology | B7199 | Withaferin A | 5mg | $360 | 2026-05-06 | Buy |
Properties
Melting point :252-253℃
alpha :D28 +125° (c = 1.30 in CHCl3)
Boiling point :680.7±55.0 °C(Predicted)
Density :1.28
Flash point :226℃
storage temp. :Desiccate at -20°C
solubility :Soluble in DMSO (up to 20 mg/ml)
pka :13.49±0.70(Predicted)
form :White solid
color :White
biological source :plant (Withania somnifera)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Major Application :food and beverages
InChIKey :DBRXOUCRJQVYJQ-CKNDUULBSA-N
SMILES :C[C@H]([C@H]1CC(C)=C(CO)C(=O)O1)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C
alpha :D28 +125° (c = 1.30 in CHCl3)
Boiling point :680.7±55.0 °C(Predicted)
Density :1.28
Flash point :226℃
storage temp. :Desiccate at -20°C
solubility :Soluble in DMSO (up to 20 mg/ml)
pka :13.49±0.70(Predicted)
form :White solid
color :White
biological source :plant (Withania somnifera)
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
Major Application :food and beverages
InChIKey :DBRXOUCRJQVYJQ-CKNDUULBSA-N
SMILES :C[C@H]([C@H]1CC(C)=C(CO)C(=O)O1)[C@H]2CC[C@H]3[C@@H]4C[C@H]5O[C@]56[C@@H](O)C=CC(=O)[C@]6(C)[C@H]4CC[C@]23C
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Up-regulation of vimentin expression is one of the hallmarks of the epithelial-mesenchymal transition that accompanies the transformation of pre-metastatic to metastatic cancer cells. Withaferin A is a steroidal lactone present in W. somnifera that at 2-25 μM has been shown to bind to and induce aggregation of vimentin intermediate filaments in cultured endothelial cells and fibroblasts, causing apoptosis. As such, it has been proposed as an anti-tumor agent to target metastatic cells that up-regulate vimentin expression. At 2 mg/kg, withaferin A exhibits potent inhibition of angiogenesis in a mouse model of injury-induced corneal neovascularization. Withaferin A can also induce perinuclear aggregates in other intermediate filament networks including peripherin, neurofilament-triplet protein, and keratin as well as disrupt the organization of microtubules and actin/microfilaments.Related product price
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Suppliers and manufacturers
BINBOBIO CO., LTD.
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Hefei Hangang Pharmaceutical Technology Co., Ltd.
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TargetMol Chemicals Inc.
Zibo Hangyu Biotechnology Development Co., Ltd
Protheragen-ING
Withaferin A
CAS:5119-48-2




