8-(2-Ethoxyphenyl)-7,8-dihydro-1,3-Dioxolo[4,5-g]quinolin-6(5H)-one
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2物価
選択条件：
ブランド
- Sigma-Aldrich Japan
パッケージ
- 5mg
- 25mg
- 生産者Sigma-Aldrich Japan
- 製品番号SML0413
- 製品説明 ≥98% (HPLC)
- 英語製品説明FQI1 ≥98% (HPLC)
- 包装単位5mg
- 価格￥16400
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番号SML0413
- 製品説明 ≥98% (HPLC)
- 英語製品説明FQI1 ≥98% (HPLC)
- 包装単位25mg
- 価格￥61300
- 更新しました2024-03-01
- 購入
| 生産者 | 製品番号 | 製品説明 | 包装単位 | 価格 | 更新時間 | 購入 |
|---|---|---|---|---|---|---|
| Sigma-Aldrich Japan | SML0413 | ≥98% (HPLC) FQI1 ≥98% (HPLC) |
5mg | ￥16400 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | SML0413 | ≥98% (HPLC) FQI1 ≥98% (HPLC) |
25mg | ￥61300 | 2024-03-01 | 購入 |
プロパティ
沸点 :463.6±45.0 °C(Predicted)
比重(密度) :1.272±0.06 g/cm3(Predicted)
貯蔵温度 :2-8°C
溶解性 :DMSO: soluble10mg/mL (clear solution)
外見 :powder
酸解離定数(Pka) :13.36±0.40(Predicted)
色 :white to beige
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
InChIKey :YKSYGLXHLSPWLB-UHFFFAOYSA-N
SMILES :O=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
比重(密度) :1.272±0.06 g/cm3(Predicted)
貯蔵温度 :2-8°C
溶解性 :DMSO: soluble10mg/mL (clear solution)
外見 :powder
酸解離定数(Pka) :13.36±0.40(Predicted)
色 :white to beige
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
InChIKey :YKSYGLXHLSPWLB-UHFFFAOYSA-N
SMILES :O=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
安全情報
| 絵表示(GHS): |
 
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| 注意喚起語: | Danger | |||||||||||||||||||||
| 危険有害性情報: |
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説明
FQI1 (599151-35-6) is an inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 μM). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3Blocks LSF-stimulated activation of DNA methyltransferase 1.4Cell permeable.関連商品価格
- (1R,2E,6S,10E,11aS,13S,14aR)-1,6,7,8,9,11a,12,13,14,14a-デカヒドロ-1,13-ジヒドロキシ-6-メチル-4H-シクロペンタ[f]オキサシクロトリデシン-4-オン
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