8-(2-Ethoxyphenyl)-7,8-dihydro-1,3-Dioxolo[4,5-g]quinolin-6(5H)-one
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- $44 - $1842
- Product name: 8-(2-Ethoxyphenyl)-7,8-dihydro-1,3-Dioxolo[4,5-g]quinolin-6(5H)-one
- CAS: 599151-35-6
- MF: C18H17NO4
- MW: 311.33
- EINECS:
- MDL Number:MFCD03632583
- Synonyms:FQI1 (FQI 1);8-(2-Ethoxyphenyl)-7,8-dihydro-1,3-Dioxolo[4,5-g]quinolin-6(5H)-one;FQI1;8-(2-ethoxyphenyl)-7,8-dihydro-5H-[1,3]dioxolo[4,5-g]quinolin-6-one;FQI1 >=98% (HPLC);1,3-Dioxolo[4,5-g]quinolin-6(5H)-one, 8-(2-ethoxyphenyl)-7,8-dihydro-
24 prices
Selected condition:
Brand
- aablocks
- ACHEMBLOCK
- AK Scientific
- AvaChem
- Axon Medchem
- Biosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
Package
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- 100MG
- Manufactureraablocks
- Product numberAA00ELW5
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99
- Packaging10mg
- Price$82
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ELW5
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99
- Packaging2mg
- Price$44
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ELW5
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99%
- Packaging5mg
- Price$50
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ELW5
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99
- Packaging25mg
- Price$147
- Updated2026-05-28
- Buy
- Manufactureraablocks
- Product numberAA00ELW5
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99
- Packaging50mg
- Price$226
- Updated2026-05-28
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD264935
- Product descriptionFQI 1 98%
- Packaging25MG
- Price$190
- Updated2026-05-27
- Buy
- ManufacturerACHEMBLOCK
- Product numberAD264935
- Product descriptionFQI 1 98%
- Packaging100MG
- Price$445
- Updated2026-05-27
- Buy
- ManufacturerAK Scientific
- Product number9467CC
- Product description8-(2-Ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
- Packaging25mg
- Price$575
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number6349
- Product descriptionFQI1 98%
- Packaging25mg
- Price$280
- Updated2026-05-22
- Buy
- ManufacturerAvaChem
- Product number6349
- Product descriptionFQI1 98%
- Packaging5mg
- Price$70
- Updated2026-05-22
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2157
- Product descriptionFQI 1
- Packaging10mg
- Price$104.5
- Updated2026-05-19
- Buy
- ManufacturerAxon Medchem
- Product numberAxon2157
- Product descriptionFQI 1
- Packaging50mg
- Price$368.5
- Updated2026-05-19
- Buy
- ManufacturerBiosynth
- Product numberZYA15135
- Product descriptionFQI1
- Packaging25mg
- Price$827.75
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberZYA15135
- Product descriptionFQI1
- Packaging50mg
- Price$1324.5
- Updated2026-06-05
- Buy
- ManufacturerBiosynth
- Product numberZYA15135
- Product descriptionFQI1
- Packaging100mg
- Price$1842
- Updated2026-06-05
- Buy
- ManufacturerCayman Chemical
- Product number23104
- Product descriptionFQI 1 ≥98%
- Packaging25mg
- Price$472
- Updated2026-04-30
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| aablocks | AA00ELW5 | 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99 | 10mg | $82 | 2026-05-28 | Buy |
| aablocks | AA00ELW5 | 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99 | 2mg | $44 | 2026-05-28 | Buy |
| aablocks | AA00ELW5 | 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99% | 5mg | $50 | 2026-05-28 | Buy |
| aablocks | AA00ELW5 | 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99 | 25mg | $147 | 2026-05-28 | Buy |
| aablocks | AA00ELW5 | 8-(2-Ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one 99 | 50mg | $226 | 2026-05-28 | Buy |
| ACHEMBLOCK | AD264935 | FQI 1 98% | 25MG | $190 | 2026-05-27 | Buy |
| ACHEMBLOCK | AD264935 | FQI 1 98% | 100MG | $445 | 2026-05-27 | Buy |
| AK Scientific | 9467CC | 8-(2-Ethoxyphenyl)-7,8-dihydro[1,3]dioxolo[4,5-g]quinolin-6(5H)-one | 25mg | $575 | 2021-12-16 | Buy |
| AvaChem | 6349 | FQI1 98% | 25mg | $280 | 2026-05-22 | Buy |
| AvaChem | 6349 | FQI1 98% | 5mg | $70 | 2026-05-22 | Buy |
| Axon Medchem | Axon2157 | FQI 1 | 10mg | $104.5 | 2026-05-19 | Buy |
| Axon Medchem | Axon2157 | FQI 1 | 50mg | $368.5 | 2026-05-19 | Buy |
| Biosynth | ZYA15135 | FQI1 | 25mg | $827.75 | 2026-06-05 | Buy |
| Biosynth | ZYA15135 | FQI1 | 50mg | $1324.5 | 2026-06-05 | Buy |
| Biosynth | ZYA15135 | FQI1 | 100mg | $1842 | 2026-06-05 | Buy |
| Cayman Chemical | 23104 | FQI 1 ≥98% | 25mg | $472 | 2026-04-30 | Buy |
Properties
Boiling point :463.6±45.0 °C(Predicted)
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
pka :13.36±0.40(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
InChIKey :YKSYGLXHLSPWLB-UHFFFAOYSA-N
SMILES :O=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
Density :1.272±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL (clear solution)
form :powder
pka :13.36±0.40(Predicted)
color :white to beige
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 3 months.
InChI :1S/C18H17NO4/c1-2-21-15-6-4-3-5-11(15)12-8-18(20)19-14-9-17-16(7-13(12)14)22-10-23-17/h3-7,9,12H,2,8,10H2,1H3,(H,19,20)
InChIKey :YKSYGLXHLSPWLB-UHFFFAOYSA-N
SMILES :O=C1CC(C2=CC=CC=C2OCC)C3=CC4=C(OCO4)C=C3N1
Safety Information
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Description
FQI1 (599151-35-6) is an inhibitor of transcription factor LSF specifically targeting its DNA binding and corresponding transcriptional activity (IC50=2.1 μM). Rapidly induces apoptosis in an aggressive hepatocellular carcinoma (HCC) cell line and dramatically inhibits tumor growth in a mouse xenograft model with no general tissue cytotoxicity.1,2In human HCC cells, FQI1 induced mitotic arrest with an accompanying increase in cyclin B1.3Blocks LSF-stimulated activation of DNA methyltransferase 1.4Cell permeable.More related product prices
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