カフェイン-D3(7-メチル-D3)

プロパティ

安全情報

説明

Caffeine-d3 is deuterated caffeine and intended for use as an internal standard for the quantification of caffeine by GC- or LC-MS.

Caffeine is a naturally occurring central nervous system stimulant belonging to the methylxanthine class and is widely recognized as the most utilized psychoactive stimulant worldwide. Caffeine's primary mechanism of action involves its effects on adenosine receptors in the brain. Being both fat- and water-soluble component, caffeine easily crosses the blood-brain barrier and antagonizes all 4 adenosine receptor subtypes (A1, A2a, A2b, and A3). The antagonism of the A2a receptor is particularly responsible for caffeine's wakefulness effects. Caffeine increases renal blood flow, glomerular filtration, and sodium excretion, resulting in diuresis. Additionally, caffeine is a potent stimulator of gastric acid secretion and gastrointestinal motility.