34316-15-9 Basic information More..
Product Name:Chelerythrine
Synonyms:1,2-Dimethoxy-N-methyl-[1,3]benzodioxolo[5,6-c]phenanthridinium chloride;CHELERYTHRINE(TODDALINE)(RG);1,2-dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridinium;chelerythrine/toddaline;1,2-Dimethoxy-12-methyl[1,3]benzodioxolo[5,6-c]phenanthridin-12-ium;2,3-(Epoxymethanoxy)-5-methyl-7,8-dimethoxybenzo[c]phenanthridine-5-ium;Einecs 251-930-0;helerythrine
CAS:34316-15-9
MF:C21H18NO4+
MW:348.37192
EINECS:251-930-0
Mol File:34316-15-9.mol
34316-15-9

Use

Chelerythrine chloride is the chloride form of Chelerythrine chloride which is a benzophenanthridine alkaloid isolated from the plant Chelidonium majus (greater celandine). It is a kind of potent, selective, and cell-permeable protein kinase C inhibitor, an efficient antagonist of G-protein-coupled CB1 receptors, and an independent activator of MAPK pathways. It has a wide range of biological activities including antiplatelet, anti-inflammatory, antibacterial and antitumor effects. It has reported of that it is capable of inducing apoptosis in HL-60 human promyelocytic leukemia cells and several other cancer cell lines. The underlying mechanism is through its effects of inhibiting the binding of BclXL to Bax or Bad.

Chelerythrine manufacturers

  • Chelerythrine
  • 2023-02-24
  • CAS:34316-15-9
  • Min. Order: 5mg
  • Purity: ≥98%(HPLC)
  • Supply Ability: 10 g
  • chelerythrine
  • $10.00
  • 2021-07-02
  • CAS:34316-15-9
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
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