212118-77-9 Basic information More..
Product Name:FLASH
Synonyms:4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;LuMio Green;FLUORESCEIN ARSENICAL HELIX BINDER;FLASH;FLASH-EDT2;FLASH Fluorescein arsenical helix binder;fluorescein bis-arsenide;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy-
CAS:212118-77-9
MF:C24H18As2O5S4
MW:664.5
EINECS:
Mol File:212118-77-9.mol
212118-77-9

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The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin.

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