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| Product Name: | FLASH | | Synonyms: | 4',5'-Bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxyspiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one;LuMio Green;FLUORESCEIN ARSENICAL HELIX BINDER;FLASH;FLASH-EDT2;FLASH
Fluorescein arsenical helix binder;fluorescein bis-arsenide;Spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one, 4',5'-bis(1,3,2-dithiarsolan-2-yl)-3',6'-dihydroxy- | | CAS: | 212118-77-9 | | MF: | C24H18As2O5S4 | | MW: | 664.5 | | EINECS: | | | Product Categories: | Fluorescent Labels & Indicators;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 212118-77-9.mol |  |
| | FLASH Chemical Properties |
| storage temp. | Store at -20°C,protect from light | | solubility | DMF: 15 mg/ml; DMSO: 20 mg/ml; DMSO:PBS (pH 7.2) (1:10): 0.09 mg/ml | | form | A crystalline solid | | color | White to light yellow | | InChI | InChI=1S/C24H18As2O5S4/c27-17-7-5-15-21(19(17)25-32-9-10-33-25)30-22-16(6-8-18(28)20(22)26-34-11-12-35-26)24(15)14-4-2-1-3-13(14)23(29)31-24/h1-8,27-28H,9-12H2 | | InChIKey | AJNUQUGWNQHQDJ-UHFFFAOYSA-N | | SMILES | C12(C3=C(C([As]4SCCS4)=C(O)C=C3)OC3=C1C=CC(O)=C3[As]1SCCS1)C1=C(C=CC=C1)C(=O)O2 |
| | FLASH Usage And Synthesis |
| Chemical Properties | White to Pale Orange Solid | | Uses | The Fluorescein Arsenical Hairpin Binder (FlAsH) method is presented for fluorescence labeling of proteins in living cells. Labeling proteins with the membrane-permeant fluorogenic biarsenical dye fluorescein arsenical hairpin binder-ethanedithiol (FlAsH-EDT2). The membrane-permeant fluorogenic biarsenicals FlAsH-EDT2 and ReAsH-EDT2 can be prepared in good yields by a straightforward two-step procedure from the inexpensive precursor dyes fluorescein and resorufin. |
| | FLASH Preparation Products And Raw materials |
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