88321-09-9 Basic information More..
Product Name:EST
Synonyms:(2S,3S)-3-[[[(1S)-3-Methyl-1-[[(3-Methylbutyl)aMino]carbonyl]butyl]aMino]carbonyl]-2-oxiranecarboxylic acid ethyl ester;(2S,3S)-trans-Epoxysuccinyl-L-leucylaMido-3-Methylbutane ethyl ester, EST;(2S,3S)-ethyl 3-(((S)-1-(isopentylaMino)-4-Methyl-1-oxopentan-2-yl)carbaMoyl)oxirane-2-carboxylate;E-64-D(LOXISTATINE);Estate;oxistatin;E64d,E-64d;E-64(Trans-Epoxysuccinyl-L-Leucylamido-(4-Guanidino)Butane)
CAS:88321-09-9
MF:C17H30N2O5
MW:342.43
EINECS:
Mol File:88321-09-9.mol
88321-09-9

Use

E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to in terfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.

EST manufacturers

  • Aloxistatin
  • US $36.00-122.00 / mg
  • 2026-04-21
  • CAS:88321-09-9
  • Min. Order:
  • Purity: 99.69%
  • Supply Ability: 10g
  • EST
  • US $7.00 / KG
  • 2019-07-14
  • CAS: 88321-09-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
  • EST
  • US $7.00 / KG
  • 2019-07-10
  • CAS: 88321-09-9
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100KG
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