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Properties

Melting point:: 126.2°C

Boiling point:: 477.88°C (rough estimate)

Density: 1.0657 (rough estimate)

refractive index: 1.5800 (estimate)

storage temp.: -20°C

solubility: Soluble in DMSO, DMF or ethanol

form: White solid

pka: 13.32±0.40(Predicted)

color: Fine needles from EtOH

biological source: synthetic (organic)

Stability:: Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.

InChI: 1S/C17H30N2O5/c1-6-23-17(22)14-13(24-14)16(21)19-12(9-11(4)5)15(20)18-8-7-10(2)3/h10-14H,6-9H2,1-5H3,(H,18,20)(H,19,21)/t12-,13-,14-/m0/s1

InChIKey: SRVFFFJZQVENJC-IHRRRGAJSA-N

SMILES: N([C@@H](CC(C)C)C(=O)NCCC(C)C)C(=O)[C@H]1O[C@@H]1C(=O)OCC

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H315-H319-H335

Precautionary statements: P261-P280a-P304+P340-P305+P351+P338-P405-P501a

Hazard Codes: Xi

Risk Statements: 36/37/38

Safety Statements: 26-36-24/25

RIDADR: 3077

WGK Germany: 2

RTECS: RR0404300

HS Code: 29242990

Storage Class: 11 - Combustible Solids

Toxicity: cyt-ham:lng 200 mg/L IYKEDH 17,815,86

Use

E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to in terfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.

You can find EST suppliers, manufacturers, and distributors from countries such as CHINA, United States and the United Kingdom here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.