Lck Inhibitor

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Company Name: Absin Bioscience Inc.  
Tel: 13761418683
Email: fengmj@univ-bio.com
Products Intro: Cas:847950-09-8
ProductName:Lck Inhibitor
Purity: >98% | Package: 5mg;10mg;50mg
Company Name: Cayman Chemical Company  
Tel: 800-364-9897
Email: sales@caymanchem.com
Products Intro: Cas:847950-09-8
ProductName:LCK Inhibitor
Company Name: Jinan Jiuli Biotechnology Co. , Ltd.  
Tel: 15865264761
Email: 486064515@qq.com
Products Intro: Cas:847950-09-8
ProductName:Lck Inhibitor
Purity: 98% | Package: 500mg；1g；5g
Company Name: RD International Technology Co., Limited  
Tel: 18024082417
Email: market@ubiochem.com
Products Intro: Cas:847950-09-8
ProductName:Lck Inhibitor
Purity: 5mg;10mg;50mg;100mg;250mg;500mg;1g | Package: 5mg;10mg;50mg;100mg;250mg;500mg;1g
Company Name: Wuhan Topule Biopharmaceutical Co., Ltd
Tel: +86-18327326525
Email: masar@topule.com
Products Intro: Cas:847950-09-8
ProductName:Lck inhibitor
Purity: 98%+ | Package: 100mg;1g;500g | CustNote: Topule Company operates with integrity and has its own laboratory, which supports packaging and customization. Payment will be made after the product has passed third-party testing

Lck Inhibitor manufacturers

  • Inhibitor
  • Inhibitor pictures
  • $19.00
  • 2024-05-11
  • CAS:
  • Min. Order: 1T
  • Purity: 98%
  • Supply Ability: 20T
Lck Inhibitor Basic information
Product Name:Lck Inhibitor
Synonyms:PyriMido[5',4':5,6]pyriMido[1,2-a]benziMidazol-5(6H)-one, 6-(2,6-diMethylphenyl)-2-[[4-(4-Methyl-1-piperazinyl)phenyl]aMino]-;Lck Inhibitor;6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one;6-(2,6-Dimethylphenyl)-2-[[4-(4-methyl-1-pyrimido[5',4':5,6]pyrimido[1,2-a]benzimidazol-5(6H)-one;TC-S 7003 (Lck Inhibitor);Lck Inhibitor 25;6-(2,6-Dimethylphenyl)-2-((4-(4-methylpiperazin-1-yl)phenyl)amino)benzo[4,5]imidazo[1,2-a]pyrimido[5,4-e]pyrimidin-5(6H)-one
CAS:847950-09-8
MF:C31H30N8O
MW:530.62
EINECS:
Product Categories:
Mol File:847950-09-8.mol
Lck Inhibitor Structure
Lck Inhibitor Chemical Properties
Boiling point 809.1±75.0 °C(Predicted)
density 1.36±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility Soluble in DMSO
form crystalline solid
pka7.87±0.42(Predicted)
color Light yellow to yellow
Safety Information
MSDS Information
Lck Inhibitor Usage And Synthesis
UsesTC-S 7003 is a novel, potent and orally active inhibitor of Lymphocyte Specific Kinase (Lck).
in vivo

Lck inhibitor (0-60 mg/kg; oral once daily; from day 9 to day 17) showed a dose-dependent inhibition of arthritis[1].
Lck inhibitor (5 mg/kg oral) treatment showed Cmax, AUC0-∞, tmax, and F% were 82 ng/mL, 862 ng h/mL, and 17%, respectively[1].

Animal Model:Male Lewis rat (adjuvant-inducedarthritis model) [1]
Dosage:0, 30, and 60 mg/kg
Administration:Po; once daily; from day 9 today 17
Result:Showed a dose-dependent inhibition of arthritis, with an ED50 estimated at 24 mg/kg.
Animal Model:Sprague-Dawley Rats[1]
Dosage:Po (Pharmacokinetic Analysis)
Administration:5 mg/kg
Result:The Cmax, AUC0-∞, tmax and F% were 82 ng/mL, 862 ng h/mL, and 17%, respectively.
storageStore at -20°C
Lck Inhibitor Preparation Products And Raw materials
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