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| | Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- Basic information |
| | Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- Chemical Properties |
| Boiling point | 623.7±65.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | pka | 15.72±0.50(Predicted) |
| | Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- Usage And Synthesis |
| Description | A1B11 is a SIRT2-selective inhibitor. | | Uses | A1B11 is a selective SIRT inhibitor (SIRT2:IC50=5.3 μM) that can be used in the study of neurodegenerative diseases[1]. | | IC 50 | SIRT2: 5.3 μM (IC50) | | References | [1] Tatum P R, et al. Identification of novel SIRT2-selective inhibitors using a click chemistry approach[J]. Bioorganic & medicinal chemistry letters, 2014, 24(8): 1871-1874. DOI:10.1016/j.bmcl.2014.03.026 |
| | Benzamide, 2-[[3-[1-(2-cyclopentylethyl)-1H-1,2,3-triazol-4-yl]phenyl]amino]- Preparation Products And Raw materials |
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