2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2)

Company Name:	Tianjin Kailiqi Biotechnology Co., Ltd.
Tel:	15076683720
Email:	klq@cw-bio.com

Company Name:	Beijing Jin Ming Biotechnology Co., Ltd.
Tel:	010-60605840
Email:	psaitong@jm-bio.com

2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2) manufacturers

2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2) Basic information

Product Name:	2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2)
Synonyms:	2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2);DC07090 Dihydrochloride;DC-07090 Dihydrochloride,DC07090 Dihydrochloride;4-(Oxazolo[4,5-b]pyridin-2-yl)-N-(pyridin-2-ylmethyl)aniline dihydrochloride
CAS:	1158264-37-9
MF:	C18H15ClN4O
MW:	338.8
EINECS:
Product Categories:
Mol File:	1158264-37-9.mol

2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2) Chemical Properties

form	Solid
color	Light yellow to yellow

Safety Information

MSDS Information

2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2) Usage And Synthesis

Description	DC07090 Dihydrochloride is a novel potent inhibitor against human enterovirus 71 3C protease.
Uses	DC07090 dihydrochloride is a low toxicity, potent, reversible and competitive non-peptidyl human enterovirus 71 3C protease inhibitor with an IC50 and a Ki value for 21.72 μM and 23.29 μM. DC07090 dihydrochloride could also inhibit coxsackievirus A16 (CVA16) replication with an EC50 value of 27.76 μM[1].
References	[1] Ma GH, et al. Identification and biochemical characterization of DC07090 as a novel potent small molecule inhibitor against human enterovirus 71 3C protease by structure-based virtual screening. Eur J Med Chem. 2016 Nov 29;124:981-991. DOI:10.1016/j.ejmech.2016.10.019

2-Pyridinemethanamine, N-(4-oxazolo[4,5-b]pyridin-2-ylphenyl)-, hydrochloride (1:2) Preparation Products And Raw materials

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