Ricinelaidicacid manufacturers
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| | Ricinelaidicacid Basic information |
| Product Name: | Ricinelaidicacid | | Synonyms: | (12R,9E)-12-Hydroxy-9-octadecenoic acid;9-trans-12-Hydroxyoctadecenoic acid;9-Octadecenoic acid, 12-hydroxy-, (9E,12R)- | | CAS: | 540-12-5 | | MF: | C18H34O3 | | MW: | 298.46 | | EINECS: | | | Product Categories: | | | Mol File: | 540-12-5.mol |  |
| | Ricinelaidicacid Chemical Properties |
| Melting point | 51~52 1) | | refractive index | - | | storage temp. | Store at -20°C | | solubility | DMF: 3 mg/ml; DMSO: 2 mg/ml; Ethanol: miscible; PBS (pH 7.2): 2 mg/ml |
| | Ricinelaidicacid Usage And Synthesis |
| Uses | Ricinelaidic acid, a 12-hydroxy fatty acid，is a leukotriene B4 (LTB4) receptor antagonist with the Ki of 2 μM in porcine neutrophil membranes. Ricinelaidic acid inhibits chemotaxis and calcium flux induced by LTB4 in isolated human neutrophils (IC50=10 and 7 μM, respectively). Ricinelaidic acid inhibits bronchoconstriction induced by LTB4 in rats[1]. | | Definition | ChEBI: A straight-chain, 18:1, long-chain fatty acid having a trans- double bond at position 9 and an R-oriented hydroxy group at position 12. | | References | [1] Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995;52(5):293-297. DOI:10.1016/0952-3278(95)90029-2 |
| | Ricinelaidicacid Preparation Products And Raw materials |
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