1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro-

Request For Quotation
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Suppliers list
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Company Name: Nanchang Tianzhen Biotechnology Co., Ltd  
Tel: 13758194781 13173652190
Email: 522013271@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 4008200310 15002144251
Email: marketing@tsbiochem.com
Company Name: YantaiBio  
Tel: 13758194781; 13758194781
Email: 764619768@qq.com
Company Name: Shanghai Yanfen Biochemical Technology Co.,LTD  
Tel: 17721070236
Email: yanfen2026@126.com

1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- manufacturers

  • FAPI-74
  • FAPI-74 pictures
  • 2025-06-07
  • CAS:2374782-76-8
  • Min. Order: 10mg
  • Purity: >95.00%
  • Supply Ability: 10mg
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Basic information
Product Name:1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro-
Synonyms:1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro-;NOTA-FAPI-74;(S)-2,2′-(7-(2-(4-(3-((4-((2-(2-cyanopyrrolidin-1-yl)-2-oxoethyl)carbamoyl)quinolin-6-yl)oxy) propyl)piperazin-1-yl)-2-oxoethyl)-1,4,7-triazonane-1,4-diyl)diacetic acid
CAS:2374782-76-8
MF:C36H49N9O8
MW:735.83
EINECS:
Product Categories:
Mol File:2374782-76-8.mol
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Structure
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Chemical Properties
Boiling point 1061.7±65.0 °C(Predicted)
density 1.41±0.1 g/cm3(Predicted)
pka1.82±0.10(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Usage And Synthesis
UsesFAPI-74 is a PET (positron emission tomography) tracer targeting the fibroblast activation protein (FAP). FAPI-74 can be used for FAP-positive tumor research[1][2].
References[1] Uwe Haberkorn, et al. Fap inhibitor. Patent, WO2019154886A1.
[2] Giesel FL, et al. FAPI-74 PET/CT Using Either 18F-AlF or Cold-Kit 68Ga Labeling: Biodistribution, Radiation Dosimetry, and Tumor Delineation in Lung Cancer Patients. J Nucl Med. 2021 Feb;62(2):201-207. DOI:10.2967/jnumed.120.245084
[3] Liu Y, et al. Fibroblast activation protein targeted therapy using [177Lu]FAPI-46 compared with [225Ac]FAPI-46 in a pancreatic cancer model. Eur J Nucl Med Mol Imaging. 2022 Feb;49(3):871-880. DOI:10.1007/s00259-021-05554-2
1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro- Preparation Products And Raw materials
Tag:1H-1,4,7-Triazonine-1,4(5H)-diacetic acid, 7-[2-[4-[3-[[4-[[[2-[(2S)-2-cyano-1-pyrrolidinyl]-2-oxoethyl]amino]carbonyl]-6-quinolinyl]oxy]propyl]-1-piperazinyl]-2-oxoethyl]hexahydro-(2374782-76-8) Related Product Information
ARI-3144 Anti-cancer compound library Sibrotuzumab Anti-Mouse FAP Antibody (73.3) OncoFAP-GlyPro-MMAE NTFAPI