3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine manufacturers
- KAAD-Cyclopamine
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- $2570.00
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2026-06-11
- CAS:306387-90-6
- Purity:
- Supply Ability: 10g
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| | 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Basic information |
| Product Name: | 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine | | Synonyms: | 3-Keto-N-aMinoethyl-N'-aMinocaproyldihydrocinnaMoyl CyclopaMine, >80%;Benzenepropanamide, N-[6-[[2-[(3'R,3'aS,6'S,6aS,6bS,7'aR,2'R,11aS,11bR)-1,2,3,3',3'a,4,5',6,6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3',6',10,11b-tetramethyl-3-oxospiro[9H-benzo[a]fluorene-9,2'(4'H)-furo[3,2-b]pyridin]-4'-yl]ethyl]amino]-6-oxohexyl]-;KAAD Cyclopamine,KAADCyclopamine;3-Keto-N-aminoethyl-N’-aminocaproyldihydrocinnamoyl Cyclopamine | | CAS: | 306387-90-6 | | MF: | C44H63N3O4 | | MW: | 697.999 | | EINECS: | | | Product Categories: | Inhibitors;Steroids;Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids | | Mol File: | 306387-90-6.mol |  |
| | 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Chemical Properties |
| Boiling point | 875.6±65.0 °C(Predicted) | | density | 1.15±0.1 g/cm3(Predicted) | | storage temp. | Hygroscopic, -20°C Freezer, Under Inert Atmosphere | | solubility | Chloroform: Slightly soluble; Methanol: Slightly soluble | | form | A solid | | pka | 16.10±0.46(Predicted) | | color | White to light yellow | | CAS DataBase Reference | 306387-90-6 |
| | 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Usage And Synthesis |
| Chemical Properties | Pale Yellow Solid | | Uses | Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects of oncogenic mutations in Smoothened and Patched.1 The KAAD-Cyclopamine has shown 10-20 fold higher potency than cyclopamine in inhibition of -Galactosidase expression in p2Ptch-1- cells, with similar or lower toxicity.KAAD-Cyclopamine compound is unstable in solution. | | Uses | Cyclopamine demonstrates teratogenic properties and has been shown to reverse effects ofoncogenic mutations in Smoothened and Patched.1 The KAAD derivative has shown 10-20 fold higher potency than cyclopamine in inhibition of -Galactosidase expression i |
| | 3-Keto-N-aminoethyl-Naminocaproyldihydrocinnamoyl Cyclopamine Preparation Products And Raw materials |
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