2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]-

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2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Suppliers list
Company Name: Shanghai Beckham Medical Technology Co., Ltd  
Tel: 13816613772
Email: huahero21@sina.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- manufacturers

  • FGFR4-IN-11
  • FGFR4-IN-11 pictures
  • $2500.00
  • 2026-07-27
  • CAS:2396664-85-8
  • Purity:
  • Supply Ability: 10g
2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Basic information
Product Name:2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]-
Synonyms:2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]-;FGFR4-IN-11
CAS:2396664-85-8
MF:C29H29N5O5
MW:527.57
EINECS:
Product Categories:
Mol File:2396664-85-8.mol
2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Structure
2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Chemical Properties
density 1.334±0.06 g/cm3(Predicted)
pka12.49±0.40(Predicted)
Safety Information
MSDS Information
2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Usage And Synthesis
UsesFGFR4-IN-11 (Compound 30) is a potent, selective, covalent FGFR4 inhibitor with an IC50 of 2.1 nM. FGFR4-IN-11 significantly inhibits the FGF19/FGFR4 signaling pathway and shows antitumor activity[1].
IC 50FGFR4: 2.1 nM (IC50)
References[1] Zhong Z, et al. Discovery of Novel 7-Azaindole Derivatives as Selective Covalent Fibroblast Growth Factor Receptor 4 Inhibitors for the Treatment of Hepatocellular Carcinoma. J Med Chem. 2022 May 26;65(10):7278-7295. DOI:10.1021/acs.jmedchem.2c00255
2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]- Preparation Products And Raw materials
Tag:2-Propenamide, N-[2-[[3-(3,5-dimethoxybenzoyl)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]-5-(4-morpholinyl)phenyl]-(2396664-85-8) Related Product Information
FGFR-1 alpha (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-2 BETA (IIIB) Protein, HUMAN (HEK293, HIS) FGFR-3 beta (iiic) protein, human (biotinylated, HEK293, His-AVI) FGFR-4 Protein, HUMAN (HEK293, HIS) Futibatinib Formononetin