1142407-60-0

Request For Quotation
1142407-60-0 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: +1-781-999-5354; +1-00000000000
Email: marketing@targetmol.com
Company Name: Jinan Ruisi Pharmaceutical Technology Co., LTD  
Tel: 0531-0531-69900633 19963472814
Email: changyuan20@163.com
Company Name: Shanghai Dexuan Pharmaceutical Technology Co., Ltd  
Tel: dexuanyiyao@126.com
Email: dexuanyiyao@126.com
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn

1142407-60-0 manufacturers

  • P 218
  • P 218 pictures
  • $129.00
  • 2026-04-20
  • CAS:1142407-60-0
  • Purity: 99.93%
  • Supply Ability: 10g
1142407-60-0 Basic information
Product Name:1142407-60-0
Synonyms:P 218;3-(2-(3-((2,4-diamino-6-ethylpyrimidin-5-yl)oxy)propoxy)phenyl)propanoic acid hydrochloride
CAS:1142407-60-0
MF:C18H25ClN4O4
MW:396.87
EINECS:
Product Categories:
Mol File:1142407-60-0.mol
1142407-60-0 Structure
1142407-60-0 Chemical Properties
Safety Information
MSDS Information
1142407-60-0 Usage And Synthesis
UsesDHFR-IN-5 hydrochloride is a potent and orally active dihydrofolate reductase (DHFR) inhibitor with a Ki value of 0.54 nM for quadruple mutant Plasmodium falciparum DHFR. DHFR-IN-5 hydrochloride shows anti-malaria activity[1].
References[1] Yuthavong Y, et al. Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised target. Proc Natl Acad Sci U S A. 2012 Oct 16;109(42):16823-8. DOI:10.1073/pnas.1204556109
1142407-60-0 Preparation Products And Raw materials
Tag:1142407-60-0(1142407-60-0) Related Product Information
Benzenepropanoic acid, 2-[3-[(2,4-diamino-6-ethyl-5-pyrimidinyl)oxy]propoxy]- 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-(1-ethylpropyl)-8-methyl- CB 3705 10-formyldihydrofolate Piritrexim DAMPA Methyl Ester