Ara-C triphosphate

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Ara-C triphosphate Basic information
Product Name:Ara-C triphosphate
Synonyms:Ara-C triphosphate;Arabinofuranosylcytosine Triphosphate;Ara-cytidine-5'-triphosphate (ara-CTP) (aqueous solution);ara-Cytidine-5'-triphosphate (ara-CTP);2(1H)-Pyrimidinone, 4-amino-1-[5-O-[hydroxy[[hydroxy(phosphonooxy)phosphinyl]oxy]phosphinyl]-β-D-arabinofuranosyl]-;Cytarabine triphosphate;ara-CTP·Na3;Ara-cytidine-5''-triphosphate (ara-CTP) (aqueous solution), DNA synthesis inhibitor
CAS:13191-15-6
MF:C9H16N3O14P3
MW:483.16
EINECS:
Product Categories:
Mol File:13191-15-6.mol
Ara-C triphosphate Structure
Ara-C triphosphate Chemical Properties
Boiling point 849.2±75.0 °C(Predicted)
density 2.50±0.1 g/cm3(Predicted)
pka0.97±0.50(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Ara-C triphosphate Usage And Synthesis
UsesCytarabine triphosphate (Ara-CTP), an active metabolite of Cytarabine, is a competitive inhibitor of DNA synthesis. Intracellular Cytarabine triphosphate levels can be used to predict chemosensitivity of leukemic blasts to Cytarabine[1].
References[1] Anderson E, et, al. Intracellular cytarabine triphosphate in circulating blasts post-treatment predicts remission status in patients with acute myeloid leukemia. Exp Hematol. 2019 Jun;74:13-18.e3. DOI:10.1016/j.exphem.2019.04.005
Ara-C triphosphate Preparation Products And Raw materials
Tag:Ara-C triphosphate(13191-15-6) Related Product Information
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