isoleucyl-lysyl-valyl-alanyl-valine manufacturers
- Laminin-1 peptide
-
- $33.00
-
2024-10-18
- CAS:131167-89-0
- Min. Order: 1Box
- Purity: 99.99%
- Supply Ability: 10000000000
|
| | isoleucyl-lysyl-valyl-alanyl-valine Basic information |
| Product Name: | isoleucyl-lysyl-valyl-alanyl-valine | | Synonyms: | isoleucyl-lysyl-valyl-alanyl-valine;Laminin-1 peptide;L-Isoleucyl-L-lysyl-L-valyl-L-alanyl-L-valine;H-Ile-Lys-Val-Ala-Val-OH;L-Valine, L-isoleucyl-L-lysyl-L-valyl-L-alanyl-;Laminin α-1 Chain (2099-2103) (human) | | CAS: | 131167-89-0 | | MF: | C25H48N6O6 | | MW: | 528.69 | | EINECS: | | | Product Categories: | | | Mol File: | 131167-89-0.mol |  |
| | isoleucyl-lysyl-valyl-alanyl-valine Chemical Properties |
| form | Solid | | color | White to off-white | | Sequence | H-Ile-Lys-Val-Ala-Val-OH |
| | isoleucyl-lysyl-valyl-alanyl-valine Usage And Synthesis |
| Uses | H-Ile-Lys-Val-Ala-Val-OH is one of the most potent active sites of laminin-1. H-Ile-Lys-Val-Ala-Val-OH promotes cell adhesion, neurite outgrowth, and tumor growth. H-Ile-Lys-Val-Ala-Val-OH stimulates BMMSC population growth and proliferation by activating MAPK/ERK1/2 and PI3K/Akt signalling pathways[1][2]. | | IC 50 | ERK1; ERK2; Akt | | References | [1] Nomizu M, et al. The all-D-configuration segment containing the IKVAV sequence of laminin A chain has similar activities to the all-L-peptide in vitro and in vivo. J Biol Chem. 1992 Jul 15;267(20):14118-21. PMID:1629212
[2] Li B, et al. IKVAV regulates ERK1/2 and Akt signalling pathways in BMMSC population growth and proliferation. Cell Prolif. 2014 Apr;47(2):133-45. DOI:10.1111/cpr.12094 |
| | isoleucyl-lysyl-valyl-alanyl-valine Preparation Products And Raw materials |
|