| Company Name: |
Biolab Reagents |
| Tel: |
027-65279366 18108604356 |
| Email: |
products@biolabreagent.com |
| Company Name: |
ACROBiosystems |
| Tel: |
13121935750 |
| Email: |
jiaxin.zhao@acrobiosystems.com |
|
| | PC cell-derived growth factor Basic information |
| Product Name: | PC cell-derived growth factor | | Synonyms: | PC cell-derived growth factor;Progranulin mouse;PEPI;Proepithelin;Progranulin from mouse;Activation-inducible TNF-related ligand;Progranulin rat;Tim-4 (human): FC (human) | | CAS: | 139316-59-9 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![PC cell-derived growth factor Structure]() |
| | PC cell-derived growth factor Chemical Properties |
| storage temp. | -20°C | | form | lyophilized | | color | white | | biological source | rat |
| WGK Germany | WGK 2 | | Storage Class | 12 - Non Combustible Liquids |
| | PC cell-derived growth factor Usage And Synthesis |
| Uses | Progranulin (PGRN) is a widely expressed pluripotent growth factor which plays a role in processes such as development, wound repair and inflammation by activating signaling cascades that control cell cycle progression and cell motility. Its function in the central nervous system is of interest, as mutations in the PGRN gene were found in cases of frontotemporal degeneration (FTLD). In addition, PGRN has also been linked to tumorigenesis. Progranulin is a biomarker for FTLD, other types of Alzheimer′s Disease (AD) and potentially for MCI (Mild Cognitive Impairment). Additionally, PGRN is described as a new ligand of TNF receptors and a potential therapeutic against inflammatory disease like arthritis. |
| | PC cell-derived growth factor Preparation Products And Raw materials |
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