tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH

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tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH manufacturers
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH Basic information
Product Name:tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH
Synonyms:tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH;L-Phenylalanine, N-[N-[N-[N-[N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl]-L-leucyl]-D-phenylalanyl]-L-leucyl]- (9CI);N Boc Phe Leu Phe Leu Phe,inhibit,Inhibitor,NBocPheLeuPheLeuPhe;Boc-DPhe-Leu-DPhe-Leu-Phe
CAS:148182-34-7
MF:C44H59N5O8
MW:785.97
EINECS:
Product Categories:
Mol File:148182-34-7.mol
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH Structure
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH Chemical Properties
Boiling point 1043.2±65.0 °C(Predicted)
density 1.167±0.06 g/cm3(Predicted)
pka3.51±0.10(Predicted)
form Solid
color White to off-white
SequenceBoc-Phe-Leu-Phe-Leu-Phe-OH
Safety Information
MSDS Information
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH Usage And Synthesis
UsesBoc-FLFLF is a formyl peptide receptor 1 (FPR1) antagonist, which increases pain effects and inhibits antinociceptive activity of annexin[1][2].
References[1] Schepetkin IA, et al. Antagonism of human formyl peptide receptor 1 (FPR1) by chromones and related isoflavones. Biochem Pharmacol. 2014 Dec 15;92(4):627-41. DOI:10.1016/j.bcp.2014.09.027
[2] Pei L, et al. Annexin 1 exerts anti-nociceptive effects after peripheral inflammatory pain through formyl-peptide-receptor-like 1 in rat dorsal root ganglion. Br J Anaesth. 2011 Dec;107(6):948-58. DOI:10.1093/bja/aer299
tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH Preparation Products And Raw materials
Tag:tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH(148182-34-7) Related Product Information
L-Leucine, N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanyl-L-phenylalanyl- tert-butyloxycarbonyl-phenylalanyl-leucyl-phenylalanyl-leucyl-phenylalanyl-OH (αS,3S)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-oxo-α-(phenylmethyl)-1-pyrroli… Z-Glu-Phe-OH IKZFNIAMQFYRSM-DHIUTWEWSA-N Z-Ile-Phe-OH