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| | Tyramide alkyne Basic information |
| Product Name: | Tyramide alkyne | | Synonyms: | Tyramide alkyne;5-Hexynamide, N-[2-(4-hydroxyphenyl)ethyl]-;N-(4-Hydroxyphenethyl)hex-5-ynamide | | CAS: | 2230051-33-7 | | MF: | C14H17NO2 | | MW: | 231.29 | | EINECS: | | | Product Categories: | | | Mol File: | 2230051-33-7.mol |  |
| | Tyramide alkyne Chemical Properties |
| Boiling point | 469.978±35.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.104±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | -10 to -25°C | | solubility | DMSO: 2mg/mL, clear | | pka | 10.009±0.15(predicted) | | form | Solid-Liquid Mixture | | color | White to off-white |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| | Tyramide alkyne Usage And Synthesis |
| Uses | Tyramide alkyne is an alternative labeling substrate that can be coupled to detection or enrichment moieties via a Copper-catalyzed Azide/Alkyne Cycloaddition (CuAAC) “click” reaction. Tyramide alkyne can be used for ascorbate peroxidase 2 (APEX2) labeling[1]. | | Biological Activity | Tyramide alkyne (Alkyne-phenol 1) is a cell penetrant and highly efficient clickable ascorbate peroxidase 2 (APEX2) substrate th at significantly improves APEX-labeling efficiency in intact yeast cells. Tyramide alkyne enable biotin-independent detection of labeled proteins. | | References | [1] Ganapathy US, et al. Compartment-Specific Labeling of Bacterial Periplasmic Proteins by Peroxidase-Mediated Biotinylation. ACS Infect Dis. 2018 Jun 8;4(6):918-925. DOI:10.1021/acsinfecdis.8b00044 |
| | Tyramide alkyne Preparation Products And Raw materials |
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