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migrastatin manufacturers
- Migrastatin
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- $1890.00
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2026-05-11
- CAS:314245-65-3
- Purity:
- Supply Ability: 10g
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| | migrastatin Basic information |
| Product Name: | migrastatin | | Synonyms: | migrastatin;2,6-Piperidinedione, 4-[(5S)-5-[(2R,3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxooxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl]- | | CAS: | 314245-65-3 | | MF: | C27H39NO7 | | MW: | 489.6 | | EINECS: | | | Product Categories: | | | Mol File: | 314245-65-3.mol |  |
| | migrastatin Chemical Properties |
| storage temp. | -20°C | | solubility | DMF: soluble,DMSO: soluble,Methanol: soluble | | form | A solid |
| | migrastatin Usage And Synthesis |
| Uses | Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2]. | | Definition | ChEBI: A 14-membered macrolide which is isolated from Streptomyces sp.MK929-43F1 and inhibits cell migration of human esophageal cancer EC17 cells and mouse melanona B16 cells. | | References | [1] Montoro-García S, et al. Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells. J Mol Med (Berl). 2020;98(3):383-394. DOI:10.1007/s00109-020-01877-z
[2] Nakae K, et al. Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1. Taxonomy, fermentation, isolation and biological activities. J Antibiot (Tokyo). 2000;53(10):1130-1136. DOI:10.7164/antibiotics.53.1130 |
| | migrastatin Preparation Products And Raw materials |
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