| Company Name: |
Cayman Chemical Company
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| Tel: |
800-364-9897 |
| Email: |
sales@caymanchem.com |
| Products Intro: |
Product Name:(±)5-HETE lactone
CAS:81517-87-5
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| | 5-hydroxyeicosatetraenoic acid lactone Basic information |
| Product Name: | 5-hydroxyeicosatetraenoic acid lactone | | Synonyms: | 5-hydroxyeicosatetraenoic acid lactone;6-[(1E,3Z,6Z,9Z)-pentadeca-1,3,6,9-tetraenyl]oxan-2-one;2H-Pyran-2-one, tetrahydro-6-(1E,3Z,6Z,9Z)-1,3,6,9-pentadecatetraen-1-yl- | | CAS: | 81517-87-5 | | MF: | C20H30O2 | | MW: | 302.45 | | EINECS: | | | Product Categories: | | | Mol File: | 81517-87-5.mol |  |
| | 5-hydroxyeicosatetraenoic acid lactone Chemical Properties |
| Boiling point | 445.7±34.0 °C(Predicted) | | density | 0.979±0.06 g/cm3(Predicted) | | solubility | DMF: 50 mg/ml
DMSO: 50 mg/ml
Ethanol: 50 mg/mlPBS pH 7.2: 1 mg/ml | | form | Clear to light-yellow liquid. |
| | 5-hydroxyeicosatetraenoic acid lactone Usage And Synthesis |
| Uses | (±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation[1][2]. | | References | [1] Tao C, et al. Reactivity of tricarbonyl (pentadienyl) iron (1+) cations: enantioselective synthesis of 5-HETE methyl ester[J]. The Journal of Organic Chemistry, 1993, 58(8): 2134-2143.
[2] Picardo C M. The hydrolysis of 5-HETE lactone by paraoxonase 1 and its stability in serum[M]. 2007.
[3] F. A. J. KERDESKY. ChemInform Abstract: Synthesis and 5-Lipoxygenase Inhibitory Activity of 5-Hydroperoxy- 6,8,11,14-eicosatetraenoic Acid Analogues.[J]. ChemInform, 1987, 18 50. DOI: 10.1002/chin.198750355 |
| | 5-hydroxyeicosatetraenoic acid lactone Preparation Products And Raw materials |
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