FKBP51F67V-selective antagonist Ligand2 manufacturers
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| | FKBP51F67V-selective antagonist Ligand2 Basic information |
| Product Name: | FKBP51F67V-selective antagonist Ligand2 | | Synonyms: | FKBP51F67V-selective antagonist Ligand2;2-Piperidinecarboxylic acid, 1-[(2S)-1-oxo-2-(3,4,5-trimethoxyphenyl)-4-penten-1-yl]-, (1R)-3-(3,4-dimethoxyphenyl)-1-[3-[2-(4-morpholinyl)ethoxy]phenyl]propyl ester, (2S)- | | CAS: | 1680228-76-5 | | MF: | C43H56N2O10 | | MW: | 760.91 | | EINECS: | | | Product Categories: | | | Mol File: | 1680228-76-5.mol |  |
| | FKBP51F67V-selective antagonist Ligand2 Chemical Properties |
| Boiling point | 843.895±65.00 °C(Press: 760.00 Torr)(predicted) | | density | 1.166±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | pka | 6.435±0.10(predicted) |
| | FKBP51F67V-selective antagonist Ligand2 Usage And Synthesis |
| Uses | FKBP51F67V-selective antagonist Ligand2 (example 3-3) is a potent FKBP51 F67V-selective antagonist ligand. FKBP51F67V-selective antagonist Ligand2 reverses the anxiogenic phenotype induced by overexpression of FKBP51 F67V in the amygdala. FKBP51F67V-selective antagonist Ligand2 binds to FKBP51 F67V, but not to wild-type FKBP51 or FKBP52[1]. | | References | [1] Steffen GAALI, et al. Selective fkbp51 ligands for treatment of psychiatric disorders. Patent, WO2015039758A1. |
| | FKBP51F67V-selective antagonist Ligand2 Preparation Products And Raw materials |
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