E3 ligase Ligand 13

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E3 ligase Ligand 13 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
E3 ligase Ligand 13 Basic information
Product Name:E3 ligase Ligand 13
Synonyms:E3 ligase Ligand 13;D-Leucine, N-[(2R,3S)-3-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-2-hydroxy-1-oxo-4-phenylbutyl]-
CAS:2701565-75-3
MF:C31H34N2O6
MW:530.61
EINECS:
Product Categories:
Mol File:2701565-75-3.mol
E3 ligase Ligand 13 Structure
E3 ligase Ligand 13 Chemical Properties
Boiling point 815.760±65.00 °C(Press: 760.00 Torr)(predicted)
density 1.253±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka3.369±0.10(predicted)
Safety Information
MSDS Information
E3 ligase Ligand 13 Usage And Synthesis
UsesE3 ligase Ligand 13 is a ligand for E3 ubiquitin ligase. E3 ligase Ligand 13 can be connected to the ligand for protein by a linker to form PROTACs. PROTACs are inducers of ubiquitination-mediated degradation of cancer-promoting proteins[1].
IC 50IAP
References[1] Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575. DOI:10.1021/acs.jmedchem.7b00168
E3 ligase Ligand 13 Preparation Products And Raw materials
Tag:E3 ligase Ligand 13(2701565-75-3) Related Product Information
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