4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo-

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4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo- Basic information
Product Name:4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo-
Synonyms:4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo-;Rhodadyn C10, cell-permeable dynamin I inhibitor;Rhodady C10
CAS:1367579-04-1
MF:C17H22N2O2S2
MW:350.5
EINECS:
Product Categories:
Mol File:1367579-04-1.mol
4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo- Structure
4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo- Chemical Properties
Melting point 92-94 °C
Boiling point 490.7±55.0 °C(predicted)
density 1.25±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka9.30±0.28(predicted)
Safety Information
MSDS Information
4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo- Usage And Synthesis
UsesRhodady C10 (Compound C10) is a dynamin I GTPase inhibitor. Rhodady C10 blocks receptor-mediated endocytosis (IC50: 7 μM). Dynamin is involved in clathrin-independent endocytosis, phagocytosis, and caveolae internalization[1].
References[1] Robertson MJ, et al. The Rhodadyns, a New Class of Small Molecule Inhibitors of Dynamin GTPase Activity. ACS Med Chem Lett. 2012 Mar 26;3(5):352-6. DOI:10.1021/ml200284s
4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo- Preparation Products And Raw materials
Tag:4-Thiazolidinone, 5-[[4-[3-(dimethylamino)propoxy]phenyl]methylene]-3-ethyl-2-thioxo-(1367579-04-1) Related Product Information
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