COX-2-IN-47

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COX-2-IN-47 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:COX-2-IN-47
CAS:2043670-02-4
Package:50mg/RMB 13800
COX-2-IN-47 Basic information
Product Name:COX-2-IN-47
Synonyms:COX-2-IN-47;Acetic acid, 2-[4-[4,5-dihydro-5-(4-methoxyphenyl)-1H-pyrazol-3-yl]phenoxy]-
CAS:2043670-02-4
MF:C18H18N2O4
MW:326.35
EINECS:
Product Categories:
Mol File:2043670-02-4.mol
COX-2-IN-47 Structure
COX-2-IN-47 Chemical Properties
Boiling point 530.340±60.00 °C(Press: 760.00 Torr)(predicted)
density 1.290±0.14 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted)
pka2.834±0.10(predicted)
Safety Information
MSDS Information
COX-2-IN-47 Usage And Synthesis
UsesCOX-2-IN-47 (compound 6c ) is a selective COX-2 inhibitor with IC50 value of 0.03 μM. COX-2-IN-47 has antiedema activity[1].
IC 50COX-2: 0.03 μM (IC50)
References[1] Elgohary MK, et al. Novel anti-inflammatory agents featuring phenoxy acetic acid moiety as a pharmacophore for selective COX-2 inhibitors: Synthesis, biological evaluation, histopathological examination and molecular modeling investigation. Bioorg Chem. 2024 Nov;152:107727. DOI:10.1016/j.bioorg.2024.107727
COX-2-IN-47 Preparation Products And Raw materials
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