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| | 6-Amino-1,3-benzodioxole-5-carboxylic acid Basic information |
| | 6-Amino-1,3-benzodioxole-5-carboxylic acid Chemical Properties |
| Melting point | 176-178 °C | | Boiling point | 387.9±42.0 °C(Predicted) | | density | 1.569±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | 2.35±0.20(Predicted) | | Appearance | Yellow to brown Solid |
| | 6-Amino-1,3-benzodioxole-5-carboxylic acid Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 6-aminobenzo[d][1,3]dioxole-5-carboxylic acid from methyl 6-aminobenzo[d][1,3]dioxole-5-carboxylate: Sodium hydroxide (2.95 g, 73.8 mmol) was added to water (75 mL), and stirred until completely dissolved. Methyl 6-aminobenzo[d][1,3]dioxole-5-carboxylate (12.0 g, 61.5 mmol) was then added and the reaction mixture was heated to 90°C and stirred for 2 hours. After completion of the reaction, the reaction mixture was cooled with ice water and the pH was adjusted to 2 with concentrated hydrochloric acid to precipitate a solid. The mixture was stirred thoroughly and filtered, the filter cake was washed with water and dried to give 6-aminobenzo[d][1,3]dioxole-5-carboxylic acid (7.2 g, 65% yield). | | References | [1] Patent: CN104557955, 2017, B. Location in patent: Paragraph 0152; 0156 |
| | 6-Amino-1,3-benzodioxole-5-carboxylic acid Preparation Products And Raw materials |
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