2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester

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2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester manufacturers

  • aPKC-I
  • aPKC-I pictures
  • $2500.00
  • 2026-05-11
  • CAS:15854-12-3
  • Purity:
  • Supply Ability: 10g
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Basic information
Product Name:2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester
Synonyms:Ethyl 2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylate;2-amino-4-(3,4-dimethoxyphenyl)-3-thiophenecarboxylic acid ethyl ester;3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-, ethyl ester;aPKC-IN-1
CAS:15854-12-3
MF:C15H17NO4S
MW:307.36
EINECS:
Product Categories:
Mol File:15854-12-3.mol
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Structure
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Chemical Properties
Boiling point 437.3±45.0 °C(Predicted)
density 1.234±0.06 g/cm3(Predicted)
pka-0.29±0.10(Predicted)
form solid
InChI1S/C15H17NO4S/c1-4-20-15(17)13-10(8-21-14(13)16)9-5-6-11(18-2)12(7-9)19-3/h5-8H,4,16H2,1-3H3
InChIKeyOZWGHIQPWZHYPG-UHFFFAOYSA-N
SMILES[s]1c(c(c(c1)c2cc(c(cc2)OC)OC)C(=O)OCC)N
Safety Information
Hazard Codes Xn
Risk Statements 22-41
Safety Statements 26-39
WGK Germany 3
Storage Class11 - Combustible Solids
Hazard ClassificationsAcute Tox. 4 Oral
Eye Dam. 1
MSDS Information
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Usage And Synthesis
UsesaPKC-IN-1 (compound 1) is an atypical protein kinase C (aPKCζ) inhibitor. aPKC-IN-1 can be used for the study of a host of diseases involving increased vascular permeability and inflammation[1].
References[1] Paul M Titchenellm, et al. Synthesis and structure-activity relationships of 2-amino-3-carboxy-4-phenylthiophenes as novel atypical protein kinase C inhibitors. Bioorg Med Chem Lett. 2013 May 15;23(10):3034-8. DOI:10.1016/j.bmcl.2013.03.019
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Preparation Products And Raw materials
Preparation Products3-Thiophenecarboxylic acid, 2-amino-4-(3,4-dimethoxyphenyl)-
Tag:2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester(15854-12-3) Related Product Information
2-Amino-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester AKOS B000853 Propyl 2-amino-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate AURORA 22129 AURORA 22800 AURORA 11642 AURORA 22503 AURORA 23065 AURORA 22059 AURORA 23079 AURORA 22183 AURORA 22727 Ethyl 2-[(4-bromobenzoyl)amino]-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate Ethyl 2-(butyrylamino)-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate Ethyl 4-(3,4-dimethoxyphenyl)-2-(2-phenylacetamido)thiophene-3-carboxylate Ethyl 2-[(2-chlorobenzoyl)amino]-4-(3,4-dimethoxyphenyl)thiophene-3-carboxylate 2-(2-Chloro-acetylamino)-4-(3,4-dimethoxy-phenyl)-thiophene-3-carboxylic acid ethyl ester Ethyl 4-(3,4-dimethoxyphenyl)-2-pivalamidothiophene-3-carboxylate