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| | 1-amino-2-naphthonitrile Basic information |
| Product Name: | 1-amino-2-naphthonitrile | | Synonyms: | 1-amino-2-naphthonitrile;2-Naphthalenecarbonitrile, 1-amino-;1-amino-2-naphthalenecarbonitrile;1-Amino-2-Cyanonaphthalene;CPD0714 | | CAS: | 3100-67-2 | | MF: | C11H8N2 | | MW: | 168.19 | | EINECS: | | | Product Categories: | | | Mol File: | 3100-67-2.mol |  |
| | 1-amino-2-naphthonitrile Chemical Properties |
| Melting point | 191-192 °C(Solv: water (7732-18-5); benzene (71-43-2)) | | Boiling point | 151-152 °C(Press: 0.3 Torr) | | density | 1.22±0.1 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | pka | -0.32±0.10(Predicted) | | Appearance | Light yellow to yellow Solid |
| | 1-amino-2-naphthonitrile Usage And Synthesis |
| Synthesis | General procedure for the synthesis of 1-amino-2-cyano naphthalene from 1-nitronaphthalene and ethyl cyanoacetate: In a dry 2L reactor, 139.8 g (1.236 mol) of ethyl cyanoacetate, 29.5 g (0.453 mol) of potassium cyanide, 46.2 g (0.824 mol) of potassium hydroxide, and 920 mL of dimethylformamide were added, and dissolved with stirring at 10 °C. Stirring was continued for 20 minutes under nitrogen protection. Subsequently, the reaction mixture was heated to 60°C and the reaction was stirred for 4 hours. Upon completion of the reaction, the reaction solvent was concentrated and 600 mL of 10% aqueous sodium hydroxide solution was added and stirred under reflux conditions for 1 hour. The reaction mixture was filtered and purified by column chromatography using dichloromethane and heptane as eluents to give 50 g (yield: 60%) of the target product labeled as [Intermediate 1-a]. | | References | [1] Patent: KR2015/111106, 2015, A. Location in patent: Paragraph 0259-0262
[2] Patent: KR2016/2328, 2016, A. Location in patent: Paragraph 0476
[3] Patent: KR2015/144120, 2015, A. Location in patent: Paragraph 0310-0313
[4] Patent: KR2018/10087, 2018, A. Location in patent: Paragraph 0578-0582
[5] Pest Management Science, 2001, vol. 57, # 7, p. 625 - 632 |
| | 1-amino-2-naphthonitrile Preparation Products And Raw materials |
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