Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate

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Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Basic information
Product Name:Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate
Synonyms:METHYL (2R,3S)-2,3-DIHYDROXY-3-PHENYLPROPIONATE;methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenyl-propion;(2R,3S)-Methyl 2,3-dihydroxy-3-phenylpropanoate;methyl (2R,3S)-2,3-dihydroxy-3-phenylpropanoate;Benzenepropanoic acid, α,β-dihydroxy-, methyl ester, (αR,βS)-;Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate;Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate
CAS:122743-18-4
MF:C10H12O4
MW:196.2
EINECS:
Product Categories:Chiral Building Blocks;Esters;Organic Building Blocks
Mol File:122743-18-4.mol
Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Structure
Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Chemical Properties
Melting point 84-88 °C (lit.)
Boiling point 345.2±9.0 °C(Predicted)
density 1.266±0.06 g/cm3(Predicted)
pka12.33±0.20(Predicted)
Optical Rotation[α]23/D +31°, c = 1 in H2O
InChI1S/C10H12O4/c1-14-10(13)9(12)8(11)7-5-3-2-4-6-7/h2-6,8-9,11-12H,1H3/t8-,9+/m0/s1
InChIKeyIXDRYSIPXMREGK-DTWKUNHWSA-N
SMILESCOC(=O)[C@H](O)[C@@H](O)c1ccccc1
Safety Information
WGK Germany 3
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Usage And Synthesis
UsesMethyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate can be used as an intermediate in the synthesis of:
  • Biologically important 5-phenyl substituted Δ2-thiazolines.
  • An antidepressant, (+)-(S)-dapoxetine.
  • (R)-Cyclohexyl lactic acid, a building block required for the preparation of an E-selectin inhibitor.

Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Preparation Products And Raw materials
Tag:Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate(122743-18-4) Related Product Information
Methyl (2R,3S)-(+)-2,3-dihydroxy-3-phenylpropionate Methyl (R)-3-hydroxy-3-phenylpropanoate Methyl (2S,3R)-(-)-2,3-dihydroxy-3-phenylpropionate (R)-(+)-3-Hydroxy-3-phenylpropionic acid Benzenepropanoic acid, β-hydroxy-α-methoxy- NSC406731